Results 141 to 150 of about 6,134,485 (406)

Sequencing of Biologic Therapy in Hidradenitis Suppurativa: A Real‐World Analysis of Treatment in Over 15,000 Patients

open access: yesJEADV Clinical Practice
Background The management of moderate to severe hidradenitis suppurativa (HS) is complex with secondary failure of monoclonal antibodies frequent. Real‐world evidence regarding the treatment landscape before starting biologic therapy has been well ...
James Pham   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Prospective Comparative Study of an Oral Synbiotic and a Myoinositol-Based Herbal Supplement in Modifying Hormone Levels and the Gut Microbiome in Non-cystic Acne

open access: yesDermatology and Therapy
Introduction Acne pathogenesis is multifactorial, involving systemic factors including gut dysbiosis, hormones, and chronic inflammation. Probiotics, myoinositol, and plant-derived molecules may modulate acne by targeting these factors.
Mildred Min   +6 more
doaj   +1 more source

EGFR Activation and Ultraviolet Light-Induced Skin Carcinogenesis

open access: yesBMC Bioinformatics, 2006
BackgroundSelection of relevant genes for sample classification is a common task in most gene expression studies, where researchers try to identify the smallest possible set of genes that can still achieve good predictive performance (for instance, for ...
R. Díaz-Uriarte, S. Á. D. Andrés
semanticscholar   +1 more source

'under the skin' [PDF]

open access: yes, 2010
A short essay on the digital work of sculptor Shelagh Cluett.incorporated into the catalogue text for 'La Cabinet de Curiosities de Mademoiselle Cluoette' by Virgina ...
Stockham, Jo, Whiles, Virginia
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Fish Skin Grafts Versus Alternative Wound Dressings in Wound Care: A Systematic Review of the Literature

open access: diamond, 2023
Mohamed Mohamed-Aly Ibrahim   +5 more
openalex   +1 more source

Nuclear symmetry energy and neutron skin thickness

open access: yes, 2012
The relation between the slope of the nuclear symmetry energy at saturation density and the neutron skin thickness is investigated. Constraints on the slope of the symmetry energy are deduced from the neutron skin data obtained in experiments with ...
Centelles, M.   +3 more
core   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim   +6 more
wiley   +1 more source

Automatic fluorescence microscopic image analyzer: a novel AI-based tool for early diagnosing superficial fungal infections

open access: yesBMC Infectious Diseases
Background Superficial fungal infections (SFIs) are highly prevalent globally, affecting approximately 20–25% of the population. Their diverse and often non-specific clinical manifestations necessitate accurate and timely laboratory diagnosis ...
Wenjing He   +3 more
doaj   +1 more source

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