Results 31 to 40 of about 522,886 (274)

Secretogranin II influences the assembly and function of MHC class I in melanoma

Experimental Hematology & Oncology, 2023
Melanoma is the deadliest form of skin cancer showing rising incidence over the past years. New insights into the mechanisms of melanoma progression contributed to the development of novel treatment options, such as immunotherapies.
Tamara Steinfass, Juliane Poelchen, Qian Sun, Giovanni Mastrogiulio, Daniel Novak, Marlene Vierthaler, Sandra Pardo, Aniello Federico, Laura Hüser, Thomas Hielscher, Rafael Carretero, Rienk Offringa, Peter Altevogt, Viktor Umansky, Jochen Utikal   +14 more
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Effects of Retinol, Natural Pea Peptide and Antioxidant Blend in a Topical Formulation: In Vitro and Clinical Evidence

Dermatology and Therapy
Introduction Retinol has a long history of treating skin conditions, including photoaging. However, skin irritation with repeated use of retinol is well documented.
Brian Cook, Melanie Riggs, K. C. Holley, Helen Knaggs, Ganesh Diwakar, Edwin D. Lephart   +5 more
doaj   +1 more source

Evaluation of the efficacy and safety of ionic liquids containing ketoconazole in patients with tinea pedis: A randomized controlled clinical trial

Bioengineering & Translational Medicine, 2023
Ionic liquids (ILs) loading ketoconazole (KCZ) have shown better efficacy on rats with tinea pedis than the marketed Daktarin® but clinical studies are still lacking.
Xiying Wu, Min Shen, Huan Wang, Xue He, Jingwen Tan, Ruiping Wang, Lianjuan Yang, Hong Yang, Jianping Qi, Zhongjian Chen, Quangang Zhu   +10 more
doaj   +1 more source

Nuclear symmetry energy and neutron skin thickness [PDF]

Acta Physica Polonica B Vol. 43, No. 2, February 2012, page 209, 2012
The relation between the slope of the nuclear symmetry energy at saturation density and the neutron skin thickness is investigated. Constraints on the slope of the symmetry energy are deduced from the neutron skin data obtained in experiments with antiprotonic atoms. Two types of neutron skin are distinguished: the "surface" and the "bulk".
arxiv   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

A case of vitiligo regression in a patient with psoriasis and psoriatic arthritis receiving adalimumab therapy

Современная ревматология, 2021
The article discusses the common pathogenetic pathways of autoimmune skin diseases – psoriasis and vitiligo. Currently proposed treatments for vitiligo do not significantly reduce or completely restore skin pigmentation. The use of adalimumab for 6 years
N. S. Rudneva, E. V. Natarova, V. N. Sorotskaya, T. G. Sadunashvili   +3 more
doaj   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Challenges documenting racial disparities in Merkel cell carcinoma

Cancer Biology & Therapy, 2022
Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer that predominantly impacts White patients. Overall incidence and the proportion of minority patients with MCC are both rising.
Mackenzie R. Martin, Noreen Mohsin, Serena Vilasi, Danielle Reed, Isaac Brownell   +4 more
doaj   +1 more source

On Diseases of the Skin [PDF]

The American Journal of the Medical Sciences
6th American from the fifth and revised London edition. ; xix, [33]-694 p.
openaire   +4 more sources