Results 31 to 40 of about 4,250,920 (342)

A Microbiome-Based Index for Assessing Skin Health and Treatment Effects for Atopic Dermatitis in Children. [PDF]

, 2019
A quantitative and objective indicator for skin health via the microbiome is of great interest for personalized skin care, but differences among skin sites and across human populations can make this goal challenging.
Callewaert, Chris, Huang, Shi, Jing, Gongchao, Knight, Rob, Li, Huiying, Liu, Jiquan, Niu, Yueqing, Smith, Ed, Su, Xiaoquan, Sun, Zheng, Wei, Karl, Xu, Jian, Yang, Ming, Yue, Feng, Zhao, Helen, Zhu, Pengfei   +15 more
core   +4 more sources

Melanoma patients with immune-related adverse events after immune checkpoint inhibitors are characterized by a distinct immunological phenotype of circulating T cells and M-MDSCs

OncoImmunology, 2023
Treatment with immune checkpoint inhibitors (ICIs) has improved the prognosis of melanoma patients. However, ICIs can cause an overactivation of the immune system followed by diverse immunological side effects known as immune-related adverse events (irAE)
Alisa Lepper, Rebekka Bitsch, Feyza Gül Özbay Kurt, Ihor Arkhypov, Samantha Lasser, Jochen Utikal, Viktor Umansky   +6 more
doaj   +1 more source

A subset of methylated CpG sites differentiate psoriatic from normal skin. [PDF]

, 2012
Psoriasis is a chronic inflammatory immune-mediated disorder affecting the skin and other organs including joints. Over 1,300 transcripts are altered in psoriatic involved skin compared with normal skin.
Bowcock, Anne M, Cao, Li, Duan, Shenghui, Joyce, Cailin E, Liao, Wilson, Liu, Ying, Martin, Ann, Menter, Alan, Roberson, Elisha DO, Ryan, Caitriona   +9 more
core   +1 more source

The immunohistochemical analysis of fibronectin, collagen type III, laminin, and cytokeratin 5 in putrified skin [PDF]

, 1993
Fibronectin, collagen type III, laminin, and cytokeratin 5 were visualized in normal skin and in skin showing early or advanced signs of autolytic decomposition to prove whether the immunohistochemical analysis of these antigens can provide useful ...
Betz, P., Eisenmenger, Wolfgang, Nerlich, A., Penning, R., Tübel, J., Wilske, J.   +5 more
core   +1 more source

Patients with melanoma of unknown primary show better outcome under immune checkpoint inhibitor therapy than patients with known primary: preliminary results

OncoImmunology, 2019
Background: Melanoma of unknown primary (MUP) is an uncommon clinical subtype of melanoma of known primary (MKP). Objectives: We aimed to compare treatment outcomes of MUP and MKP patients who had undergone therapy with immune checkpoint inhibitors (ICPI)
Thilo Gambichler, Maria Chatzipantazi, Ulrike Schröter, E. Stockfleth, Cansu Gedik   +4 more
doaj   +1 more source

Fingertip skin models for analysis of the haptic perception of textiles [PDF]

, 2014
This paper presents finite element models of the fingertip skin which have been created to simulate the contact of textile objects with the skin to gain a better understanding of the perception of textiles through the skin, the so-called hand of textiles.
Ciesielska-Wrobel, Izabela, Grabowska, Katarzyna, Van Langenhove, Lieva   +2 more
core   +2 more sources

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

Large Area Electronic Skin [PDF]

, 2017
Technological advances have enabled various approaches for developing artificial organs such as bionic eyes, artificial ears, and lungs etc. Recently electronics (e-skin) or tactile skin has attracted increasing attention for its potential to detect ...
Dahiya, Ravinder
core   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Effects of Retinol, Natural Pea Peptide and Antioxidant Blend in a Topical Formulation: In Vitro and Clinical Evidence

Dermatology and Therapy
Introduction Retinol has a long history of treating skin conditions, including photoaging. However, skin irritation with repeated use of retinol is well documented.
Brian Cook, Melanie Riggs, K. C. Holley, Helen Knaggs, Ganesh Diwakar, Edwin D. Lephart   +5 more
doaj   +1 more source