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Skin Absorption of Anions: Part Two. Skin Absorption of Halide Ions
Pharmaceutical Research, 2016The purpose of the study was to sort skin penetration of anions with respect to their properties and to assess their mechanisms of penetration.Aqueous solutions of halides at two concentrations were prepared and quantitative penetration studies were carried out for 24 h using Franz diffusion cells. The iodide permeation was also measured after blocking
Paweloszek, Raphael+5 more
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The Absorption of Mercury Through the Skin
Journal of the American Pharmaceutical Association (Scientific ed.), 1949The penetration of mercury through the skin of rabbits has been assayed in the case of two mercury ointments which differ only in that one contains resorcinol. The assay consisted in measuring the mercury concentration of the kidneys after twenty-four hours of topical application. The kidneys of rabbits exposed to the resorcinol-containing ointment had
E.D. Robinson, A. Bass
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PERMEABILITY AND ABSORPTIVITY OF THE SKIN
Archives of Dermatology, 1939Because of the systemic and local effects of the cutaneous application of various medicaments, the permeability and absorptivity of the skin are of particular importance to the dermatologist. As far back as 1809 Mussey1proved that after topical application of certain drugs to the unbroken skin these drugs were found in the urine, and in 1901 ...
Joseph Jordan Eller, Shirley Wolff
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Absorption of lead through the skin
Toxicology, 1976Absorption of lead through the skin was studied by comparing the effect produced by lead naphthenate or lead acetate solution, when coated on the skin of rats, with data obtained from subcutaneous injections of these solutions. Body weight and liver size and weight decreased in the case of rats receiving the subcutaneous dose. delta-Aminolevulinic acid
Jørgen Clausen, Suresh Chandra Rastogi
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Skin absorption in vitro of glycol ethers
International Archives of Occupational and Environmental Health, 1999The increased use of glycol ethers (GEs) for water-based paints and cleaning products, combined with a lack of information about many of these products, particularly with regard to the effects of percutaneous exposure, led us to evaluate the skin absorption rates of a group of glycol ethers in vitro.Skin permeation was calculated using the Franz cell ...
LARESE FILON, FRANCESCA+6 more
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Models for Skin Absorption and Skin Toxicity Testing [PDF]
This chapter includes information about models for skin absorption testing and skin toxicity testing in a condensed form. At first, the structure and function of human skin is described discussing the contribution of the different skin layers and skin appendages to skin absorption. Moreover, various skin absorption pathways are discussed.
Claus-Michael Lehr+4 more
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Absorption of chemicals through compromised skin
International Archives of Occupational and Environmental Health, 2009Skin is an important route of entry for many chemicals in the work place. To assess systemic uptake of a chemical in contact with the skin, quantitative information on dermal absorption rates of chemicals is needed. Absorption rates are mainly obtained from studies performed with intact, healthy skin.
Sanja Kezic, Jesper Bo Nielsen
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The Absorption of X Rays by the Skin
The British Journal of Radiology, 1937In a recent paper1 by Molesworth and Riddle, it was asserted that the angle of incidence of a beam of X rays has little or no practical influence upon the dose actually absorbed in tissue lying immediately below the surface irradiated. As it is known that the intensity of a beam of X rays is only very slightly reduced in its passage through the skin ...
Henry L. Brose, E. H. Molesworth
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Basic Mathematics in Skin Absorption
2017Frequently, analysis of skin absorption does not only require the careful evaluation of experimental data but also the fundamental understanding of underlying physics to apply the appropriate mathematical concepts to attain insight into transport kinetics. This chapter will introduce the basic mathematics which are necessary to evaluate skin permeation
Claus-Michael Lehr+3 more
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