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Skin Absorption of Anions: Part Two. Skin Absorption of Halide Ions

Pharmaceutical Research, 2016
The purpose of the study was to sort skin penetration of anions with respect to their properties and to assess their mechanisms of penetration.Aqueous solutions of halides at two concentrations were prepared and quantitative penetration studies were carried out for 24 h using Franz diffusion cells. The iodide permeation was also measured after blocking
Paweloszek, Raphael   +5 more
openaire   +6 more sources

The Absorption of Mercury Through the Skin

Journal of the American Pharmaceutical Association (Scientific ed.), 1949
The penetration of mercury through the skin of rabbits has been assayed in the case of two mercury ointments which differ only in that one contains resorcinol. The assay consisted in measuring the mercury concentration of the kidneys after twenty-four hours of topical application. The kidneys of rabbits exposed to the resorcinol-containing ointment had
E.D. Robinson, A. Bass
openaire   +3 more sources

PERMEABILITY AND ABSORPTIVITY OF THE SKIN

Archives of Dermatology, 1939
Because of the systemic and local effects of the cutaneous application of various medicaments, the permeability and absorptivity of the skin are of particular importance to the dermatologist. As far back as 1809 Mussey1proved that after topical application of certain drugs to the unbroken skin these drugs were found in the urine, and in 1901 ...
Joseph Jordan Eller, Shirley Wolff
openaire   +2 more sources

Absorption of lead through the skin

Toxicology, 1976
Absorption of lead through the skin was studied by comparing the effect produced by lead naphthenate or lead acetate solution, when coated on the skin of rats, with data obtained from subcutaneous injections of these solutions. Body weight and liver size and weight decreased in the case of rats receiving the subcutaneous dose. delta-Aminolevulinic acid
Jørgen Clausen, Suresh Chandra Rastogi
openaire   +3 more sources

Skin absorption in vitro of glycol ethers

International Archives of Occupational and Environmental Health, 1999
The increased use of glycol ethers (GEs) for water-based paints and cleaning products, combined with a lack of information about many of these products, particularly with regard to the effects of percutaneous exposure, led us to evaluate the skin absorption rates of a group of glycol ethers in vitro.Skin permeation was calculated using the Franz cell ...
LARESE FILON, FRANCESCA   +6 more
openaire   +4 more sources

Models for Skin Absorption and Skin Toxicity Testing [PDF]

open access: possible, 2007
This chapter includes information about models for skin absorption testing and skin toxicity testing in a condensed form. At first, the structure and function of human skin is described discussing the contribution of the different skin layers and skin appendages to skin absorption. Moreover, various skin absorption pathways are discussed.
Claus-Michael Lehr   +4 more
openaire   +1 more source

Absorption of chemicals through compromised skin

International Archives of Occupational and Environmental Health, 2009
Skin is an important route of entry for many chemicals in the work place. To assess systemic uptake of a chemical in contact with the skin, quantitative information on dermal absorption rates of chemicals is needed. Absorption rates are mainly obtained from studies performed with intact, healthy skin.
Sanja Kezic, Jesper Bo Nielsen
openaire   +3 more sources

The Absorption of X Rays by the Skin

The British Journal of Radiology, 1937
In a recent paper1 by Molesworth and Riddle, it was asserted that the angle of incidence of a beam of X rays has little or no practical influence upon the dose actually absorbed in tissue lying immediately below the surface irradiated. As it is known that the intensity of a beam of X rays is only very slightly reduced in its passage through the skin ...
Henry L. Brose, E. H. Molesworth
openaire   +2 more sources

Basic Mathematics in Skin Absorption

2017
Frequently, analysis of skin absorption does not only require the careful evaluation of experimental data but also the fundamental understanding of underlying physics to apply the appropriate mathematical concepts to attain insight into transport kinetics. This chapter will introduce the basic mathematics which are necessary to evaluate skin permeation
Claus-Michael Lehr   +3 more
openaire   +2 more sources

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