Results 301 to 310 of about 492,394 (350)
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Annales pharmaceutiques francaises, 1993
Transdermal penetration of drugs is currently much studied because it presents several attractive aspects, avoiding first past effects and offering means of immediate breaking of the therapeutic in case of hitch. But it must overcome the very efficient hindrance of the epidermal barrier.
C, Durandeau +3 more
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Transdermal penetration of drugs is currently much studied because it presents several attractive aspects, avoiding first past effects and offering means of immediate breaking of the therapeutic in case of hitch. But it must overcome the very efficient hindrance of the epidermal barrier.
C, Durandeau +3 more
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Absorption of Pesticides in a Chronic Skin Disease
Archives of Environmental Health: An International Journal, 1971The case of a 64-year-old pesticide formulator is presented. Despite the fact that the patient had no more exposure to dieldrin and several other organochlorine pesticides than his occupational associates, and that he used protective clothing, he, nonetheless, developed relatively high levels of these chemicals in his blood and tissues. The high levels
H G, Starr, N J, Clifford
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Percutaneous absorption of water in skin: a review
Reviews on Environmental Health, 2014Abstract Background: The stratum corneum has a wide variety of important functions, including host protection from foreign chemicals and bacteria, water loss prevention, and body temperature regulation. While water absorption studies on healthy intact skin are abundant, data on the percutaneous absorption of water in ...
Collin M, Blattner +3 more
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Percutaneous absorption of vapors in human skin
Cutaneous and Ocular Toxicology, 2010The absorption of vapors through the skin is an important issue because exposure of skin to chemicals in the ambient air occurs at all times. In regards to occupational health, accurately quantifying percutaneous absorption is crucial for worker health and safety.Review the available data regarding the percutaneous absorption of vapors in humans.We ...
Balvinder, Rehal, Howard, Maibach
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Critical reviews in therapeutic drug carrier systems, 1993
When we try to maximize drug flux through the skin, we usually meet major difficulties because of the impervious nature of the stratum corneum. A popular solution incorporates penetration enhancers into transdermal products. Such materials ideally possess the sole property of reversibly reducing the barrier resistance of the horny layer, allowing the ...
A C, Williams, B W, Barry
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When we try to maximize drug flux through the skin, we usually meet major difficulties because of the impervious nature of the stratum corneum. A popular solution incorporates penetration enhancers into transdermal products. Such materials ideally possess the sole property of reversibly reducing the barrier resistance of the horny layer, allowing the ...
A C, Williams, B W, Barry
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Absorption of hexavalent chromium by skin in man
Archives of Toxicology, 1981Absorption by skin of hexavalent chromium from aqueous solutions of sodium chromate in man was investigated. It was found that the amount of chromium absorbed was related to the concentration of Cr6+ in solution and to time of exposure. For 0.01, 0.1, and 0.2 molar solutions of chromium, skin absorption rates during 1 h exposure were 1.1, 6.5, and 10.0
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Models for Skin Absorption and Skin Toxicity Testing
2007This chapter includes information about models for skin absorption testing and skin toxicity testing in a condensed form. At first, the structure and function of human skin is described discussing the contribution of the different skin layers and skin appendages to skin absorption. Moreover, various skin absorption pathways are discussed.
Ulrich F. Schaefer +4 more
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Paraquat Poisoning by Skin Absorption: A Review
Human Toxicology, 1988All reported cases of paraquat poisoning by absorption through the skin are briefly reviewed. It is concluded that, while paraquat cannot be absorbed significantly through intact human skin, damage to the skin, either by paraquat itself or by other means, will permit greater systemic absorption and possibly poisoning. The lowest known concentration of
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