Results 191 to 200 of about 9,094,601 (241)
Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin+17 more
wiley +1 more source
Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim+8 more
wiley +1 more source
Loss of EPC-1/PEDF Expression During Skin Aging In Vivo [PDF]
Mary Kay Francis+5 more
openalex +1 more source
Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications
A customizable and scalable approach to fabricate flexible 3D kirigami microelectrode arrays (MEAs) featuring up to 128 shanks, including surface and penetrating electrodes designed to interact with the 3D space of neural tissue, is presented. The 3D kirigami MEAs are successfully deployed in several neural applications, both in vitro and in vivo, and ...
Marie Jung+10 more
wiley +1 more source
Early allergen exposure, skin prick responses, and atopic wheeze at age 5 in English children: a cohort study [PDF]
Paul Cullinan
openalex +1 more source
Biomimetic Dynamics of Nanoscale Groove and Ridge Topography for Stem Cell Regulation
Dynamic nanoscale groove‐ridge structures are engineered by flexibly conjugating RGD‐magnetic nanoparticles to nanogroove templates with variable groove widths at the molecular scale. Magnetic control enables cyclic switching between nanoscale groove and ridge states that modulates ligand accessibility of cellular integrins.
Hyunsik Hong+8 more
wiley +1 more source
Regional Difference in Morphological Changes in Facial Skin Surface with Aging.
Takafumi Nishijima+3 more
openalex +2 more sources
Altered Mitogen-Activated Protein Kinase Signal Transduction in Human Skin Fibroblasts During In Vitro Aging: Differential Expression of Low-Density Lipoprotein Receptor [PDF]
Chhanda Bose+2 more
openalex +1 more source
Materials Advances in Devices for Heart Disease Interventions
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra+11 more
wiley +1 more source