Results 151 to 160 of about 153,020 (257)

Impact of Social Media on Skin Cancer Prevention. [PDF]

open access: yesInt J Environ Res Public Health, 2021
De La Garza H, Maymone MBC, Vashi NA.
europepmc   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu   +11 more
wiley   +1 more source

Visual Tailoring and Skin Cancer Prevention: Comparing Personalized, Stock, and Non-Ultraviolet Images. [PDF]

open access: yesHealth Commun, 2023
Pokharel M   +5 more
europepmc   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi   +12 more
wiley   +1 more source

[Shaded places for skin cancer prevention in kindergartens and schools]. [PDF]

open access: yesBundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2022
Hanewinkel R   +4 more
europepmc   +1 more source

Targeting Lactate‐Driven Stromal Autophagy via MCT1 Disrupts the Immunosuppressive Niche and Sensitizes Pancreatic Cancer to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo   +14 more
wiley   +1 more source

Outdoor workers' perceptions of skin cancer prevention: a qualitative study. [PDF]

open access: yesAnn Work Expo Health
Ward J   +5 more
europepmc   +1 more source

Increasing Skin Cancer Prevention in Young Adults: the Cumulative Impact of Personalized UV Photography and MC1R Genetic Testing. [PDF]

open access: yesJ Cancer Educ, 2023
Wu YP   +11 more
europepmc   +1 more source

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