Results 51 to 60 of about 3,526,439 (338)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Inheritance of different undertones of onion (Allium cepa L.) dry skin color and the relationship between color and adherence

Acta Agrobotanica, 2013
The research was carried out in 1977 and 1978. The inheritance of undertones, dry skin color from light straw to brown was controlled by two additive genes. The segregation ratio obtained was 15:1 and 11:5.
Roch W. Doruchowski
doaj   +1 more source

Skin Lesion Classification Based on Surface Fractal Dimensions and Statistical Color Cluster Features Using an Ensemble of Machine Learning Techniques

Cancers, 2021
Simple Summary This study aimed to investigate the efficacy of implementation of novel skin surface fractal dimension features as an auxiliary diagnostic method for melanoma recognition.
Simona Moldovanu, F. A. Damian Michis, Keka C. Biswas, A. Culea-Florescu, L. Moraru   +4 more
semanticscholar   +1 more source

Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up [PDF]

, 2015
In the International Visible Trait Genetics (VisiGen) Consortium, we investigated the genetics of human skin color by combining a series of genome-wide association studies (GWAS) in a total of 17,262 Europeans with functional follow-up of discovered loci.
Bataille, V. (Veronique), Chaitanya, L.C. (Lakshmi), Duffy, D.L. (David), Glass, D. (Daniel), Henders, A.K. (Anjali), Hofman, A. (Albert), Hysi, P.G. (Pirro), IJcken, W.F.J. (Wilfred) van, Jacobs, L.C. (Leonie), Kayser, M.H. (Manfred), Lao Grueso, O. (Oscar), Liu, F. (Fan), Mangino, M. (Massimo), Martin, N.G. (Nicholas), Montgomery, G.W. (Grant), Nijsten, T.E.C. (Tamar), Palstra, R.-J.T.S. (Robert-Jan), Rivadeneira Ramirez, F. (Fernando), Spector, T.D. (Timothy), Sturm, R.A. (Richard A.), Uitterlinden, A.G. (André), Visser, M. (Mijke), Walsh, S. (Susan), Wollstein, A. (Andreas), Zhong, K. (Kaiyin), Zhu, G. (Gu)   +25 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Automatic segmentation of skin cancer images using adaptive color clustering [PDF]

, 2006
This paper presents the development of an adaptive image segmentation algorithm designed for the identification of the skin cancer and pigmented lesions in dermoscopy images. The key component of the developed algorithm is the Adaptive Spatial K-Means (A-
Ilea, Dana E., Whelan, Paul F.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Race/skin color and mental health disorders in Brazil: a systematic review of the literature.

Ciência & Saúde Coletiva, 2017
Mental health disorders contribute a significant burden to society. This systematic literature review aims to summarize the current state of the literature on race/skin color and mental health disorders in Brazil.
J. Smolen, E. M. D. Araújo
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

BMI Trajectories in Adulthood: The Intersection of Skin Color, Gender, and Age among African Americans

Journal of Health and Social Behavior, 2018
This study addresses three research questions critical to understanding if and how skin color shapes health among African Americans: (1) Does skin color predict trajectories of body mass index (BMI) among African Americans across ages 32 to 55?
Taylor W. Hargrove
semanticscholar   +1 more source