Results 51 to 60 of about 435,470 (309)

Ascertaining infectious disease burden through primary care clinic attendance among young Aboriginal children living in four remote communities in Western Australia. [PDF]

PLoS ONE, 2018
Infectious diseases contribute a substantial burden of ill-health in Australia's Aboriginal children. Skin infections have been shown to be common in remote Aboriginal communities, particularly in the Northern Territory, Australia.
David Hendrickx, Asha C Bowen, Julie A Marsh, Jonathan R Carapetis, Roz Walker   +4 more
doaj   +1 more source

Bacterial Skin Dysbiosis in Darier Disease

Dermatology
<b><i>Introduction:</i></b> Darier disease is a rare inherited disease with dominant skin manifestations including keratotic papules and plaques on sebaceous and flexural areas. Secondary infection of skin lesions is common, and <i>Staphylococcus aureus</i> commonly colonizes these lesions.
Reiter, Ofer, Leshem, Avner, Alexander-Shani, Rivka, Brandwein, Michael, Cohen, Yotam, Yeshurun, Algit, Ziv, Michael, Elinav, Eran, Hodak, Emmilia, Dodiuk-Gad, Roni P.   +9 more
openaire   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Skin, gut, and sand metagenomic data on placebo-controlled sandbox biodiversity intervention study

Data in Brief, 2023
The metagenomic data presented in this article are related to the published research of “A Placebo-controlled double-blinded test of the biodiversity hypothesis of immune-mediated diseases: Environmental microbial diversity elicits changes in cytokines ...
Marja I. Roslund, Anirudra Parajuli, Nan Hui, Riikka Puhakka, Mira Grönroos, Laura Soininen, Noora Nurminen, Sami Oikarinen, Ondřej Cinek, Lenka Kramná, Anna-Mari Schroderus, Olli H. Laitinen, Tuure Kinnunen, Heikki Hyöty, Aki Sinkkonen   +14 more
doaj   +1 more source

Ethnomedicine of the Kagera Region, north western Tanzania. Part 3: plants used in traditional medicine in Kikuku village, Muleba District. [PDF]

, 2012
BACKGROUND\ud \ud The Kagera region of north western Tanzania has a rich culture of traditional medicine use and practice. Traditional medicines are the mainstay of healthcare in this region and are known to support the management of many illnesses such ...
Moshi, Mainen J, Otieno, Donald F, Weisheit, Anke   +2 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

High Impetigo Burden among Pediatric Patients Reporting to the Dermatology Clinic at a Tertiary Care Center

Indian Journal of Paediatric Dermatology
Introduction: Impetigo affects mainly children from regions having resource poor settings and shows a seasonal pattern with cases increasing in hot and humid weather. Rajasthan is the most climate sensitive state of India and witnessed one of the hottest
Yashik Bansal, Rajesh Rao, Lovlesh Gopalia, Tuhina Shree, Shivani Choudhary, Anuradha Yadav   +5 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Diagnostic challenges and treatment difficulties in a patient with excoriated acne conglobata [PDF]

, 2017
Acne conglobata is a rare and severe form of acne vulgaris, characterized by the presence of comedones, papules, pustules, nodules and sometimes hematic or meliceric crusts.
Benea, Vasile, Georgescu, Simona R., Mitran, Cristina I., Mitran, Mădălina I., Sârbu, Maria I., Tampa, Mircea   +5 more
core   +4 more sources

Differentiation of keratinocytes or exposure to type 2 cytokines diminishes S. aureus internalization

mSphere
Staphylococcus aureus is a leading cause of skin and soft tissue infections. Colonization by this bacterium is increased in individuals with chronic cutaneous diseases such as atopic dermatitis, psoriasis, and bullous pemphigoid. The greater abundance of
Alexis R. Morgenstern, Liam F. Peterson, Kimberly A. Arnold, Matthew G. Brewer   +3 more
doaj   +1 more source