Results 61 to 70 of about 4,049,900 (256)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Comparing cutaneous research funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases with 2010 Global Burden of Disease results. [PDF]

PLoS ONE, 2014
ImportanceDisease burden data helps guide research prioritization.ObjectiveTo determine the extent to which grants issued by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) reflect disease burden, measured by disability ...
Chante Karimkhani, Lindsay N Boyers, David J Margolis, Mohsen Naghavi, Roderick J Hay, Hywel C Williams, Luigi Naldi, Luc E Coffeng, Martin A Weinstock, Cory A Dunnick, Hannah Pederson, Theo Vos, Christopher J L Murray, Robert P Dellavalle   +13 more
doaj   +1 more source

Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin [PDF]

, 2013
Buruli ulcer (BU), caused by Mycobacterium ulcerans is a chronic necrotizing skin disease. It usually starts with a subcutaneous nodule or plaque containing large clusters of extracellular acid-fast bacilli.
Kwabena Quenin-Fosu, Gerd Pluschke, Newman Mercy, Ruf, Marie-Thérèse, Cynthia Kwakye-Maclean (349465), Grace S. Kpeli, Asan-Ampah, Kobina, Mercy Newman (409617), Kwabena Quenin-Fosu (335716), Marie-Thérèse Ruf (2280196), Isaac Lamptey, Kwakye-Maclean Cynthia, Mercy Newman, Albert Paintsil (409614), Kpeli Grace S., Cynthia Kwakye-Maclean, Grace S. Kpeli (409612), Isaac Lamptey (409615), Dorothy Yeboah-Manu, Benjamin Anku, Pluschke, Gerd, Yeboah-Manu, Dorothy, Evelyn Owusu-Mireku, Marie-Thérèse Ruf, Dorothy Yeboah-Manu (120059), Grace S Kpeli, Anku Benjamin, Albert Paintsil, Owusu-Mireku Evelyn, Evelyn Owusu-Mireku (409613), Quenin-Fosu Kwabena, Owusu-Mireku, Evelyn, Lamptey, Isaac, Paintsil, Albert, Quenin-Fosu, Kwabena, Benjamin Anku (409616), Ruf Marie-Thérèse, Pluschke Gerd, Kwakye-Maclean, Cynthia, Gerd Pluschke (7855), Kobina Asan-Ampah (335715), Anku, Benjamin, Asan-Ampah Kobina, Yeboah-Manu Dorothy, Paintsil Albert, Kpeli, Grace S., Newman, Mercy, Lamptey Isaac, Kobina Asan-Ampah   +48 more
core   +2 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

High Impetigo Burden among Pediatric Patients Reporting to the Dermatology Clinic at a Tertiary Care Center

Indian Journal of Paediatric Dermatology
Introduction: Impetigo affects mainly children from regions having resource poor settings and shows a seasonal pattern with cases increasing in hot and humid weather. Rajasthan is the most climate sensitive state of India and witnessed one of the hottest
Yashik Bansal, Rajesh Rao, Lovlesh Gopalia, Tuhina Shree, Shivani Choudhary, Anuradha Yadav   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Ascertaining infectious disease burden through primary care clinic attendance among young Aboriginal children living in four remote communities in Western Australia. [PDF]

PLoS ONE, 2018
Infectious diseases contribute a substantial burden of ill-health in Australia's Aboriginal children. Skin infections have been shown to be common in remote Aboriginal communities, particularly in the Northern Territory, Australia.
David Hendrickx, Asha C Bowen, Julie A Marsh, Jonathan R Carapetis, Roz Walker   +4 more
doaj   +1 more source

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich, Alexis Ogdie, Alisa Stephens Shields, Peter A. Merkel, Shervin Assassi, Elana J. Bernstein, Andreea Bujor, Flavia V. Castelino, Lorinda Chung, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Melissa Griffith, Faye N. Hant, Monica L. Harding, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota J. Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Maureen D. Mayes, Zsuzsanna H. McMahan, Jerry Molitor, Duncan F. Moore, Julie Paik, Carrie Richardson, Brian Skaug, Ami A. Shah, Ankoor Shah, Virginia Steen, John M. VanBuren, Elizabeth R. Volkmann, Carleigh Zahn, Nora Sandorfi, for the CONQUER Investigators   +35 more
wiley   +1 more source

Differentiation of keratinocytes or exposure to type 2 cytokines diminishes S. aureus internalization

mSphere
Staphylococcus aureus is a leading cause of skin and soft tissue infections. Colonization by this bacterium is increased in individuals with chronic cutaneous diseases such as atopic dermatitis, psoriasis, and bullous pemphigoid. The greater abundance of
Alexis R. Morgenstern, Liam F. Peterson, Kimberly A. Arnold, Matthew G. Brewer   +3 more
doaj   +1 more source

Clinical study of common bacterial, fungal and parasitic skin diseases in cats [PDF]

Background: The skin is a large, metabolically active organ that requires significant nutrients and protein in its body. The study pointed high significant infection with fungal, scabies, alopecia, bacterial and wounds in the white color cats more than ...
Alautaish, Hassanin H. N., Saud, Zainab Abudal Hussein, Naji, Hussein Ali   +2 more
core   +1 more source