Results 181 to 190 of about 350,517 (216)

Clinical and Molecular Characteristics of <i>Streptococcus dysgalactiae</i> subsp. <i>equisimilis</i> Bacteremia in Japan. [PDF]

Open Forum Infect Dis
Matsuno T, Suzuki M, Hosoda T, Doi Y.
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Emergence of <i>Trichophyton indotineae: in vitro</i> susceptibility data from a mycology reference laboratory in Australia. [PDF]

JAC Antimicrob Resist
Roudbary M, Chen SCA, Vieira da Silva A, Beardsley J, Halliday CL.   +4 more
europepmc   +1 more source

Nicotinamide Metabolism Constrains Memory CD8+ T Cell Formation Through a Putative HS1BP3‐SIRT1‐FOXO3‐BCL6 Axis

Advanced Science, EarlyView.
ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐binding protein 3 (HS1BP3) is preferentially expressed in memory CD8+ T cells.
Siyang Wang, Xiaoqian Fan, Yifan Huang, Chang Yao, Jixing Fan, Yu Ping, Xuan Zhao, Congcong Li, Chunyi Shen, Jiqi Shan, Jinyan Liu, Shengdian Wang, Zhen Zhang, Yi Zhang   +13 more
wiley   +1 more source

Cerebrospinal Fluid Profiles Across Clinical Manifestations of Early European Lyme Neuroborreliosis. [PDF]

Open Forum Infect Dis
Ogrinc K, Bogovič P, Kastrin A, Ružić-Sabljić E, Strle F.   +4 more
europepmc   +1 more source

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

Advanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang, Ching Yin Fong, Xin Huang, Bee Luan Khoo   +3 more
wiley   +1 more source

Correction to: Cutaneous Opportunistic Mycobacterial and Fungal Infections in Adult-Onset Immunodeficiency Due to Anti-Interferon-Gamma Autoantibodies-Decoding Skin Involvement Patterns. [PDF]

Open Forum Infect Dis
europepmc   +1 more source

Stewart-Treves Syndrome Misdiagnosed as Cellulitis Following the 2023 Kahramanmaraş Earthquake. [PDF]

Infect Dis Clin Microbiol
Kapmaz M, Abik YN, Çöpür S, İrkören P, Gücer LS, Usta O, Tekin S, Ergönül Ö.   +7 more
europepmc   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Fungal Skin Infections in Cutaneous T-cell Lymphoma Patients under Mogamulizumab Treatment. [PDF]

Acta Derm Venereol
Melchers S, Gerigk M, Hedke M, Weiß C, Nicolay JP.   +4 more
europepmc   +1 more source