Faculty Profile: Herbert E. Cohn, MD, FACS [PDF]
One might say if you don’t know Dr. Herbert Cohn, you don’t really know Jefferson. Dr. Cohn arrived at Jefferson Medical College in 1951 as a medical student (JMC ’55).
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Oxidative stress in the pathogenesis of systemic scleroderma: An overview [PDF]
Systemic sclerosis (SSc) is a rare disorder of the connective tissue characterized by fibrosis of the skin, skeletal muscles and visceral organs. Additional manifestations include activation of the immune system and vascular injury. SSc causes disability
Gambardella, Lucrezia +5 more
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Diabetes Prediction Using Artificial Neural Network [PDF]
Diabetes is one of the most common diseases worldwide where a cure is not found for it yet. Annually it cost a lot of money to care for people with diabetes. Thus the most important issue is the prediction to be very accurate and to use a reliable method
Abu-Naser, Samy S. +1 more
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Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. [PDF]
PurposeThe phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has ...
Akers, Amy L +16 more
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Major Limb Amputations: A Tertiary Hospital Experience in Northwestern Tanzania. [PDF]
Major limb amputation is reported to be a major but preventable public health problem that is associated with profound economic, social and psychological effects on the patient and family especially in developing countries where the prosthetic services ...
Chalya, Phillipo L +6 more
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Progress in the use of adeno-associated viral vectors for gene therapy [PDF]
The development of safe and efficient gene transfer vectors is crucial for the success of gene therapy trials. A viral vector system promising to meet these requirements is based on the apathogenic adeno-associated virus (AAV-2), a member of the ...
Braun-Falco, M., Buning, H., Hallek, M.
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Complement system in dermatological diseases – fire under the skin
The complement system plays a key role in several dermatological diseases. Overactivation, deficiency or abnormality of the control proteins are often related to a skin disease.
Jaana Helena Panelius +4 more
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Hemangiosarcoma of the third eyelid in a horse [PDF]
A 12-year-old Belgian Warmblood mare was referred to the equine clinic of the Faculty of Veterinary Medicine (Ghent University) for a mass on the third eyelid of the right eye. The horse had been having a recurrent red-tinged ocular discharge for several
Chiers, Koen +4 more
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Endothelial senescence drives intrinsic skin aging via the neuroimmune CGRP-mast cell axis in mice
Aging is accompanied by progressive vascular dysfunction, but its effects on skin aging remain poorly understood. Although endothelial cell (EC) senescence is implicated in various age-related diseases, its specific role in dermal aging remains unclear ...
Satrio Adi Wicaksono +8 more
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Elevated serum levels of macrophage migration inhibitory factor and stem cell growth factor β in patients with idiopathic and systemic sclerosis associated pulmonary arterial hypertension. [PDF]
Pulmonary arterial hypertension (PAH) can be idiopathic or secondary to autoimmune diseases, and it represents one of the most threatening complications of systemic sclerosis (SSc).
Alessandri, Cristiano +9 more
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