Results 211 to 220 of about 3,836,410 (303)

SAPHO syndrome and pustular skin diseases: shared inflammatory circuits, divergent tissue outcomes, and the limits of a spectrum model. [PDF]

Front Immunol
Xia R, Gao K, Zhao Y, Lin Y, Yang Q, Xu W.   +5 more
europepmc   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Advances in Bioprinting to Model Immune-Mediated Skin Diseases. [PDF]

Adv Healthc Mater
Ulloa-Fernández A, Markovic M, Fernández-Pérez J, Stary G, Ovsianikov A.   +4 more
europepmc   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

'My Precious Skin'-A photo exhibition to promote awareness and destigmatization of skin diseases. [PDF]

J Eur Acad Dermatol Venereol
Näslund-Koch C, Elberling J, Skov L, Fabricius S, Zachariae C, Krontoft ASB.   +5 more
europepmc   +1 more source

Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin

Advanced Healthcare Materials, EarlyView.
Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi, Gülçin Arslan Azizoğlu, Mark R. Prausnitz   +2 more
wiley   +1 more source

Hidden immune memory niches in inflammatory skin diseases

Steele L, Foster AR, Roberts K, Admane C, Birk S, Mazin PV, Akbarnejad A, Tudor C, Rumney B, Chan HM, Olabi B, Jiang T, Rowe V, Baudry D, Hale C, Winheim E, Farr E, McWilliam J, Gambardella L, Chakala KP, Gopee NH, Binkevich A, Predeus A, Prete M, Vahidi A, O’Toole EA, Basurto-Lozada D, Horsfall D, Stephenson E, Shanmugiah VBM, Geha RS, Xavier RJ, Smith C, Mahil S, Lotfollahi M, Haniffa M.   +35 more
europepmc   +1 more source

Epigenetic Therapies for Inflammatory and Immune-Mediated Skin Diseases. [PDF]

Biomedicines
Makridou A, Elemes DI, Liakou ME, Theotokis P, Gargani S, Vakirlis E, Meditskou S, Onoufriadis A, Manthou ME, Dermitzakis I.   +9 more
europepmc   +1 more source

Tumor‐Targeted Hyaluronic Acid/Tannic Acid‐Engineered Oxygen Nanogenerators With IR780 Payloads Enable Dual‐Mode Glutathione Depletion and Effective Singlet Oxygen Generation for Melanoma Treatment

Advanced Healthcare Materials, EarlyView.
A hyaluronic acid/tannic acid‐engineered Prussian blue oxygen nanogenerator loaded with IR780 is developed to enhance melanoma phototherapy. By integrating tumor targeting, oxygen self‐supply, and dual‐mode glutathione depletion, the nanoplatform effectively overcomes hypoxia and antioxidant defenses, potentiating synergistic photothermal/photodynamic ...
Chai‐How Hsu, I‐Ju Liu, Hsiang‐Yun Chih, Tsai‐Ching Hsu, Ju‐An Liang, Chia‐Wei Kuo, Bor‐Show Tzang, Wen‐Hsuan Chiang   +7 more
wiley   +1 more source

Exploring the Role of Skin Microbiota in Autoimmune Skin Diseases from a Bidirectional Mendelian Randomization Perspective. [PDF]

Clin Cosmet Investig Dermatol
Wang J, Wang X, Tao X, Yang Q, Zhang M, Wang Y, Liu S.   +6 more
europepmc   +1 more source