Results 41 to 50 of about 1,591,119 (295)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Juventus Skin Cream : Get Brightness Your Skin Appearance!

open access: yes, 2020
Juventus Skin Cream Reviews : It is undreamed of a few years ago. That can only be assumed. I'm little. You're probably imagining, "What does this have to do with me?" Old pros don't expect anything of substance to come out of this.
Juventus Skin Cream
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Television Time among Brazilian Adolescents: Correlated Factors are Different between Boys and Girls

open access: yesThe Scientific World Journal, 2014
Objective. The aim of this study was to identify the prevalence of excess television time and verify correlated factors in adolescent males and females. Methods. This cross-sectional study included 2,105 adolescents aged from 13 to 18 years from the city
Diego Augusto Santos Silva   +3 more
doaj   +1 more source

Functioning pituitary tumours: Hints from the skin [PDF]

open access: yesRomanian Medical Journal, 2020
We introduce dermatological aspects from an endocrine point of view related to pituitary tumours that display active secretor activity. This is a short literature review. 40 papers are cited including narrative reviews and original studies.
Florica Sandru   +6 more
doaj   +1 more source

Endocannabinoids limit excessive mast cell maturation and activation in human skin [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2012
Mast cells (MCs) crucially contribute to many inflammatory diseases. However, the physiological controls preventing excessive activities of MCs in human skin are incompletely understood.Since endocannabinoids are important neuroendocrine MC modifiers, we investigated how stimulation/inhibition of cannabinoid 1 (CB1) receptors affect the biology of ...
Sugawara, Koji   +10 more
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

SESQ, a patient-reported outcome instrument addressing excess skin; report on the updated version and the validation process

open access: yes, 2023
Excess skin after weight loss is perceived as a major problem for the majority of the bariatric patients, between 68 and 90% desire additional reconstructive surgery.
Elander, Anna,   +2 more
core   +1 more source

Decreased Quality of Life in Patients Who Desire Body Contouring Surgery after Bariatric Metabolic Surgery: A Multicenter Longitudinal Analysis

open access: yesObesity Facts
Introduction: Excess skin after bariatric metabolic surgery may negatively impact quality of life (QoL). Nevertheless, not every eligible patient undergoes body contouring surgery (BCS), which may be explained by differences in QoL.
Phillip J. Dijkhorst   +6 more
doaj   +1 more source

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