Results 51 to 60 of about 3,255,281 (310)

Skin Microflora and Bacterial Infections of the Skin [PDF]

open access: yesJournal of Investigative Dermatology Symposium Proceedings, 2001
The skin is a milieu for controlled bacterial growth. Skin supports the growth of commensal bacteria, which protect the host from pathogenic bacteria. Environmental and local factors, host immunity, and organism adherence and virulence are intricately related to cutaneous infection.
Chiller, Katarina   +2 more
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Lawsonella clevelandensis: a normal flora that bites deep

open access: yesFrontiers in Cellular and Infection Microbiology
Since its formal description in 2016, Lawsonella clevelandensis—a strictly anaerobic, partially acid-fast bacterium—has been increasingly recognized as a cause of deep-seated abscesses, yet its fastidious nature and absence from routine diagnostic ...
Yun Jin   +7 more
doaj   +1 more source

An Efficient Evaluation System Accelerates α-Helical Antimicrobial Peptide Discovery and Its Application to Global Human Genome Mining

open access: yesFrontiers in Microbiology, 2022
Antimicrobial peptides (AMPs), as an important part of the innate immune system of an organism, is a kind of promising drug candidate for novel antibiotics due to their unique antibacterial mechanism.
Licheng Liu   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Case Report: A rare co-occurrence of IgA pemphigus and pyoderma gangrenosum associated with IgA-κ type monoclonal gammopathy of undetermined significance: a 19-year diagnostic and therapeutic journey

open access: yesFrontiers in Immunology
We report a complex case of neutrophilic dermatosis (ND) in a 61-year-old woman with a 19-year history of recurrent, pruritic, and painful vesiculopustular eruptions.
You Xie   +9 more
doaj   +1 more source

Alleviation of Pseudomonas aeruginosa Infection by Propeptide-Mediated Inhibition of Protease IV

open access: yesMicrobiology Spectrum, 2021
Pseudomonas aeruginosa, an opportunistic human pathogen, expresses protease IV (PIV) for infection. Since the PIV activity can be inhibited by its propeptide, we tried to alleviate the severity of P. aeruginosa infection using the purified PIV propeptide
Tae-Hyeon Kim, Xi-Hui Li, Joon-Hee Lee
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Skin and systemic infections in children with atopic dermatitis: review of the current evidence

open access: yesFrontiers in Pediatrics
Atopic dermatitis is a chronic, pruritic inflammatory skin disorder that affects approximately 2%–42% of children worldwide. Its course is frequently complicated by secondary bacterial, viral, and fungal infections, which can exacerbate disease severity ...
Rodrigo Lomelí-Valdez   +2 more
doaj   +1 more source

Interaction of skin cells with skin microbiota [PDF]

open access: yes, 2023
The interaction between skin cells and skin microbiota is complicated and not fully understood. A diverse community of microbes resides on the skin that participates in shaping its physiology. Skin microbiota can modulate skin immunity and barrier, thus,
Moinipoor, Z.
core   +1 more source

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