Assessing skin irritation potential is critical for the safety evaluation of topical drugs and other consumer products such as cosmetics. The use of advanced cellular models, as an alternative to replace animal testing in the safety evaluation for both ...
Zhengxi Wei +10 more
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The effect of washing and drying practices on skin barrier function [PDF]
Purpose: The aim of this study was to explore the potential contribution to skin damage caused by standard washing and drying techniques used in nursing.Design: An experimental cohort design was used, with healthy volunteers (n = 15) receiving 6 ...
David Voegeli, Voegeli, D.
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New possibilities for professional care of sensitive skin prone to dryness and irritation
The high need for expanding the range of dermatocosmetics with moisturizing, nourishing and anti-inflammatory action necessitates the search for new compositions with niacinamide, allantoin without components with proven allergic potential and is ...
N. V. Zilberberg
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The Phenion (R) Full-Thickness Skin Model for Percutaneous Absorption Testing [PDF]
In recent years many efforts have been made to replace dermal toxicity testing of chemicals in the animal by in vitro assays. As a member of a German research consortium, we have previously contributed to the validation of an in vitro test protocol for ...
Korting, Hans Christian +9 more
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Preparation of Polyurethane–Urea Fibers with Controlled Surface Morphology via Gel State
It is widely known that skin irritation can be induced by interactions between polymer fibers constituting clothing and the skin, leading to skin inflammation and unfavorable dermatological reactions. Thus, significant endeavors have been directed toward
Yutaka Ohsedo, Honoka Murata
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Background. Rabbit skin model was used to test skin irritation of the most commonly used cosmetic products in Jimma town, southwestern Ethiopia. The most commonly used cosmetics were Dove, Glysolid, College, Top Society, Fair and Lovely, Nivea, Lux ...
Wayessa Amasa +3 more
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Improved antibacterial activity of topical gel-based on nanosponge carrier of cinnamon oil [PDF]
Introduction: Cinnamon essential oil (CEO) is a volatile oil, obtained from Cinnamomum zeylanicum has become one of the most important natural oil due to its antimicrobial activity.
Malkiet Kaur +5 more
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New cationic nanovesicular systems containing lysine-based surfactants for topical administration: Toxicity assessment using representative skin cell lines [PDF]
Many strategies for treating diseases require the delivery of drugs into the cell cytoplasm following internalization within endosomal vesicles. Thus, compounds triggered by low pH to disrupt membranes and release endosomal contents into the cytosol are ...
Vinardell, M. Pilar +11 more
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Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention [PDF]
BackgroundAtopic dermatitis (atopic eczema) is a chronic inflammatory skin disease that has reached epidemic proportions in children worldwide and is increasing in prevalence.
Cork, Michael J. +11 more
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TiO2 Nanoparticles as a Common Component of Sunscreens: An Experimental Study of Dermal/Ocular Safety Assessment [PDF]
Background: The safety evaluations of sunscreens containing Titanium Dioxide-Nanoparticles (TiO2-NPs) were done by dermal exposure, acute dermal and eye irritation/corrosion, and skin sensitization according to the guideline for Organization for Economic
Seyedeh Maedeh Jafari +4 more
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