Results 51 to 60 of about 938,782 (286)

Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin

open access: yesAdvanced Healthcare Materials, EarlyView.
Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi   +2 more
wiley   +1 more source

IL-6, VEGF, KC and RANTES Are a Major Cause of a High Irritant Dermatitis to Phthalic Anhydride in C57BL/6 Inbred Mice

open access: yesAllergology International, 2010
Background: In previous studies, several strains of mice were used as chemical-induced skin irritation models to identify immunological hazards and elucidate the molecular and cellular mechanisms by which irritant dermatitis disease occur.
Chang-Joon Bae   +7 more
doaj   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

open access: yesAdvanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans   +7 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

An Automatic Identification System of Human Skin Irritation [PDF]

open access: yes, 2010
Quantitative characterization of human skin irritation is important but it is difficult task to be done. Recently, an identification of human skin is still doing manually.
Fadlil, Abdul; Ahmad Dahlan University
core   +1 more source

Safety assessment of female sexual hygiene product containing cannabidiol in new zealand white rabbit and clinical trial

open access: yesToxicology Reports
Cannabis is an herb known for its significant pharmacological effects. This study evaluated the safety of a female sexual hygiene product containing cannabidiol on the skin of experimental animals and humans.
Atiwut Kamudhamas   +7 more
doaj   +1 more source

Anti UV, the Sun Protection Factor (SPF), and Irritation Test of Coastal Vegetation Ricinus communis [PDF]

open access: yesBIO Web of Conferences
This study aims to test anti-UV activity, determine the SPF, and perform an irritation test on human skin from Ricinus communis leaf extract. The anti-UV and SPF values were determined using a UV-Vis Spectrophotometer.
Situmorang Easter C.H.   +7 more
doaj   +1 more source

Wearable Morphology‐Adaptive in‐Ear Device With Active Cleansing Capability for Multimodal Health Monitoring

open access: yesAdvanced Materials, EarlyView.
We present SCIENCE, an in‐ear multimodal physiological monitor featuring two key innovations. Water‐triggered morphological expansion (a 2‐mm cylinder to a 9‐mm spindle) achieves conformal adaptation across complex canal geometries. Simultaneously, active biofouling mitigation disrupts cerumen barriers, reducing sensor‐skin impedance by 20%.
Shuyun Zhuo   +3 more
wiley   +1 more source

Alternative methods for skin irritation testing: the current status : ECVAM skin irritation task force report 1

open access: yes, 1998
The ECVAM Skin Irritation Task Force was established in November 1996, primarily to prepare a report on the current status of the development and validation of alternative tests for skin irritation and corrosion and, in particular, to identify any ...
Sandt, J.J.M.   +4 more
core   +1 more source

Evaluation of a novel anti-oxidant Ubiquinol acetate (EnQ10) for its safety by in vitro methods

open access: yesHeliyon
Background: As an active form of Coenzyme Q10 (CoQ10), Ubiquinol acetate (EnQ10) is a newly developed, chemically stable, and physiologically active novel antioxidant. In addition to its anti-oxidant properties, CoQ10 is a useful cosmetic agent for human
Mohan Cheluru Umesh   +2 more
doaj   +1 more source

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