Mechanisms of cancer cell death by mutant p53-reactivating compound APR-246 [PDF]
Tumor suppressor TP53 is the most frequently mutated gene in cancer. A majority of TP53 mutations result in a mutant p53 that disrupts its DNA binding capabilities but may also acquire novel gain-of-function activities that contribute to tumor growth ...
Ceder, Sophia
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Descriptive epidemiology of vulvar and vaginal cancers in Vaud, Switzerland, 1974-1994 [PDF]
Background: To analyse trends in incidence, survival and risk of second neoplasms following vaginal and vulvar cancers using data collected by the Swiss Cancer Registry of Vaud over the 21-year period 1974-1994.
La Vecchia, C. +2 more
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Epidemiology of vulvar lichen sclerosus and its correlation with other conditions [PDF]
OBJECTIVES: To investigate some epidemiological data of lichensclerosus patients; to verify its association with other conditionsand compare these data with the literature.
Eduardo Sérgio Borges da Fonseca +5 more
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Murine Models of Splenic Marginal Zone Lymphoma: A role for Cav1? [PDF]
Dozens of murine models of indolent and aggressive B-cell lymphomas have been generated to-date. These include those manifesting chronic lymphocytic leukemia (CLL), diffuse large B-cell lymphoma (DLBCL) as well as xenografts of mantle cell lymphoma (MCL).
Cutucache, Christine E. +1 more
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Indolent lymphoma: the pathologist's viewpoint [PDF]
Indolent lymphomas have recently been the object of numerous studies, which have focused on new aspects relevant both for the better comprehension of their histogenesis and the identification of new therapeutic strategies. As marginal-zone lymphoma (MZL)
Bendandi, M. +4 more
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Intracranial epidural haematoma following surgical removal of a giant lumbosacral schwannoma: a case report and literature review. [PDF]
Postoperative intracranial epidural haematoma (EDH) is an extremely rare complication following spinal surgery, with only a handful of cases described in the literature.
Barić, Hrvoje +5 more
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The Risk of Cancer Associated with Immunosuppressive Therapy for Skin Diseases [PDF]
The possible carcinogenic risk of immunosuppressive therapies is an important issue in everyday clinical practise. Carcinogenesis is a slow multi step procedure, thus a long latency period is needed before cancer develops.
Väkevä, Liisa
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Soft tissue sarcomas of vulva [PDF]
Fifteen cases of vulvar sarcomas were studied. The most common neoplasm was leiomyosarcoma, which also had the least favorable prognosis with a tendency to develop local recurrences and disseminated hematogenous metastases.
Abell, Murray R., Davos, Irene
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Do Patients Bypass Rural Hospitals? Determinants of Inpatient Hospital Choice in Rural California [PDF]
Rural hospitals play a crucial role in providing healthcare to rural Americans, a vulnerable and underserved population; however, rural hospitals have faced threats to their financial viability and many have closed as a result.
José J Escarce, Kanika Kapur
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Prostatic adenocarcinoma with mandibular metastatic lesion : case report [PDF]
Metastatic lesions of primary tumors, which originate in different parts of the body, comprise almost 1 % of different types of oral cancers. These lesions can affect either bones or soft tissues in the maxillofacial region.
Encina Moriámez, Susana +2 more
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