Results 321 to 330 of about 1,692,764 (393)

Franz diffusion cell and its implication in skin permeation studies

Journal of Dispersion Science and Technology, 2023
Franz diffusion cell was primarily used to evaluate the permeability and stability of formulations such as topical (gels and creams) and transdermal (lipid nanoparticle formulations).
M. Kumar, Ankita Sharma, Syed Mahmood, Anil Thakur, M. A. Mirza, A. Bhatia   +5 more
semanticscholar   +1 more source

Improved skin permeation of transferosomes containing Eulophia macrobulbon extract.

Colloids and Surfaces B: Biointerfaces, 2023
Eulophia macrobulbon (EM) extract-loaded transferosomes represent an advanced approach for enhancing skin permeation of bioactive compounds. The formulations improving skin permeation and characterizations of transferosomes were studied, including ...
Sasawat Potisuwan, Nutsawadee Apichatwatana, Soravoot Rujivipat   +2 more
semanticscholar   +1 more source

Effect of lipid and edge activator concentration on development of aceclofenac-loaded transfersomes gel for transdermal application: in vitro and ex vivo skin permeation

Drug Development and Industrial Pharmacy, 2020
The present investigation focused mainly on the development of aceclofenac (AF) loaded transfersomal gel (AF-TG) to minimize the frequency of oral dosing during the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
N. Dudhipala, Riyaz Phasha Mohammed, Ahmed Adel Ali Youssef, Nagaraj Banala   +3 more
semanticscholar   +1 more source

Estimating skin permeation. The validation of five mathematical skin permeation models

Chemosphere, 1995
This study provides an analysis of the reliability of five mathematical models, simulating permeation of substances through the skin from aqueous solutions. An extensive database was generated, containing data on 123 measured permeation coefficients of 99 different chemicals and their physicochemical properties.
Wilschut, A., Berge, W.F. ten, Robinson, P.J., Mckone, T.E.   +3 more
openaire   +3 more sources

Emulgels Containing Carbopol 934P and Different Vegetable Oils for Topical Propolis Delivery: Bioadhesion, Drug Release Profile, and Ex Vivo Skin Permeation Studies

AAPS PharmSciTech, 2020
Topical administration can enable a more efficient therapy based on the improved bioavailability and patient compliance. Wounds and infections can lead to modifications of skin physiology and body protective function.
Rafaela Said dos Santos, C. F. Vecchi, H. Rosseto, Jéssica Bassi da Silva, Maria Eduarda Lima Dano, L. D. de Castro-Hoshino, M. Baesso, M. Bruschi   +7 more
semanticscholar   +1 more source

Skin Permeation of Nanoparticles: Mechanisms Involved and Critical Factors Governing Topical Drug Delivery.

Current pharmaceutical design, 2020
Transdermal route has been an ever sought-after means of drug administration, regarded as being most convenient and patient compliant. However, skin poses a great barrier to the entry of the external particles including bacteria, viruses, allergens and ...
T. U. Wani, R. Mohi-ud-din, Asmat Majeed, S. Kawoosa, F. Pottoo   +4 more
semanticscholar   +1 more source

Permeation of Steroids through Human Skin

Journal of Pharmaceutical Sciences, 1995
The permeabilities of many steroids through human skin have been previously measured and reported in the literature. Analysis of these data reveals that significant discrepancies exist between the measurements of Scheuplein et al. and those of other groups.
M E, Johnson, D, Blankschtein, R, Langer
openaire   +2 more sources

Skin permeation: The years of enlightenment

International Journal of Pharmaceutics, 2005
Considerable advances in our understanding of the mechanisms by which drugs permeate the skin barrier have been made over the past 60 years. The key publications, which have influenced the field of skin permeation research are highlighted in the present review. The methodologies commonly employed for estimation of skin permeability are discussed as are
Jonathan, Hadgraft, Majella E, Lane
openaire   +2 more sources

Formulation and characterization of glibenclamide and quercetin-loaded chitosan nanogels targeting skin permeation.

Therapeutic delivery, 2019
Aim: Our aim was to develop and characterize a nanogel formulation containing both glibenclamide and quercetin and to explore the permeation profile of this combination. Methods: Drug-loaded nanogel was prepared by ionic gelation.
D. Chellappan, Neoh Jia Yee, Bhalqish Jeet Kaur Ambar Jeet Singh, Jithendra Panneerselvam, Thiagarajan Madheswaran, Jestin Chellian, S. Satija, M. Mehta, M. Gulati, G. Gupta, K. Dua   +10 more
semanticscholar   +1 more source

Pharmacokinetics of Drug Permeation through Human Skin

Journal of Pharmaceutical Sciences, 1978
Based on sorption and permeation characteristics of scopolamine in human skin in vitro and drug elimination kinetics obtained from pharmacokinetic studies, a mathematical model was developed for estimating and optimizing the temporal pattern of scopolamine delivery from a transdermal therapeutic system through human skin in vivo.
S K, Chandrasekaran, W, Bayne, J E, Shaw
openaire   +2 more sources