Results 191 to 200 of about 69,829 (286)

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

open access: yesInterdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li   +15 more
wiley   +1 more source

Chemical-Specific T Cell Tests Aim to Bridge a Gap in Skin Sensitization Evaluation. [PDF]

open access: yesToxics
Fritsch N   +6 more
europepmc   +1 more source

Late Hypersensitivity Reactions to the BNT162b2 SARS-CoV-2 Vaccine Are Linked to Delayed Skin Sensitization and Prior Exposure to Hyaluronic Acid. [PDF]

open access: yesLife (Basel), 2022
Maoz-Segal R   +7 more
europepmc   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye   +3 more
wiley   +1 more source

Profiles of Early Life Stress and Their Interaction With Proximal Stress in Early Adulthood: A Person‐Centered Approach

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Objective Adverse effects of early life stress (ELS) exposure are well‐documented, but the joint effects of multiple exposures to different types of ELS (e.g., abuse, neglect, family dysfunction, maladaptive parenting) and their interaction with more proximal stress in adulthood remains less understood.
Juhyun Park   +3 more
wiley   +1 more source

Blocking the adverse outcome pathway of skin sensitization through a N-acetyl cysteine and lysine-loaded hydrogel. [PDF]

open access: yesJ Pharm Anal
Brites GS   +10 more
europepmc   +1 more source

Impact of a Modular Escape Game on Undergraduate and Continuing Dental Education

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Purpose This study aimed to assess the educational impact and perceived relevance of a pedagogical escape game designed to reinforce key concepts related to dental biomaterials. Methods In 2023, a modular escape game comprising four mandatory stations and one bonus station was developed and integrated into two pedagogical settings: a ...
Sara Bergman   +24 more
wiley   +1 more source

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