Results 131 to 140 of about 16,474,355 (396)
Test No. 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method
OECD Guidelines for the Testing of Chemicals, Section 4, 2021 semanticscholar +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Establishment and biological characterization of radioresistant colorectal cancer cell lines
FEBS Open Bio, EarlyView.Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu +10 more
wiley +1 more source
Comparison of cell-mediated immunity due to Leishmania infantum promastigotes and axenic amastigotes
Vaccine Research, 2018 Introduction: Leishmania infantum is the causative agent of visceral leishmaniasis (VL). Cell-mediated immunity (CMI) is required to control leishmaniases. Therefore, simple tests that can evaluate the cellular immunity of the target populations can help
A Najafi-Dastanaei +4 more
doaj
Test No. 442C: In Chemico Skin Sensitisation
OECD Guidelines for the Testing of Chemicals, Section 4, 2021 semanticscholar +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source
Test No. 406: Skin Sensitisation
OECD Guidelines for the Testing of Chemicals, Section 4, 2021 semanticscholar +1 more source
FEBS Open Bio, EarlyView.ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren +8 more
wiley +1 more source
JEADV Clinical PracticeDulaglutide is a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, which stimulates insulin release via activation of GLP‐1 receptors on pancreatic beta cells.
Leonardo Bianchi +5 more
doaj +1 more source
Fatal ampicillin-sulbactam anaphylaxis in a 34-year-old male
Journal of Allergy and Clinical Immunology: Global, 2023 A 34-year-old man receiving his first dose of ampicillin-sulbactam for osteomyelitis in a hospital setting experienced fatal drug-induced anaphylaxis.
Marielle C. Young, MD, MPH +5 more
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