Results 31 to 40 of about 284,063 (362)

Role of customised negative-pressure wound therapy in the integration of split-thickness skin grafts: A randomised control study

Indian Journal of Plastic Surgery, 2017
Background: Split-thickness skin grafting (STSG) is a time-tested technique in wound cover, but many factors lead to suboptimal graft take. Role of custom-made negative-pressure wound therapy (NPWT) is compared with conventional dress in the integration ...
Mir Mohsin, Haroon Rashid Zargar, Adil Hafeez Wani, Mohammad Inam Zaroo, Peerzada Umar Farooq Baba, Sheikh Adil Bashir, Altaf Rasool, Akram Hussain Bijli   +7 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Non‐Cultured Melanocyte‐Keratinocyte Transplantation Combined With NB‐UVB Therapy for Facial Depigmentation Induced by Skin Exfoliator: A Case Report

Clinical Case Reports
Non‐cultured melanocyte‐keratinocyte transplantation combined with narrowband ultraviolet B (NB‐UVB) therapy is a promising and well‐tolerated treatment for facial hypo‐pigmentation following scarring.
Sona Zare, Alireza Jafarzadeh, Maryam Nouri, Solmaz Zare, Mohammad Ali Nilforoushzadeh   +4 more
doaj   +1 more source

Immunology of skin transplantation

Clinics in Dermatology, 2005
Untreated viable allogeneic skin is highly immunogenic. Epidermal Langerhans migrate after transplantation out of the donor skin into the lymph node of the recipient where they can activate T cells capable to mediate rejection. Allogeneic skin is used as a temporary coverage of burn wounds, often in combination with autologous skin grafts.
Richters, C.D., Hoekstra, M.J., du Pont, J.S., Kreis, RW, Kamperdijk, E.W.   +4 more
openaire   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Dermal mesenchymal stem cells (DMSCs) inhibit skin-homing CD8+ T cell activity, a determining factor of vitiligo patients' autologous melanocytes transplantation efficiency. [PDF]

PLoS ONE, 2013
We here investigated the efficiency of autologous melanocyte transplantation of 23 vitiligo patients by focusing on perilesional skin homing CD8+ T lymphocytes, and studied the potential effect of dermal mesenchymal stem cells (DMSCs) on CD8+ T cell ...
Miao-ni Zhou, Zhi-qing Zhang, Ji-long Wu, Fu-quan Lin, Li-fang Fu, Sui-qan Wang, Cui-ping Guan, Hong-lin Wang, Aie Xu   +8 more
doaj   +1 more source

An Anhydrous Sodium Chloride Skin Preservation Model for Studies on Keratinocytes Grafting into the Wounds

Pharmaceutics, 2021
Background. Human skin is needed for covering large body areas lost by trauma. The shortcomings of contemporary methods of skin storage are limited preservation time and high immunogenicity if allogeneic. Methods.
Anna Domaszewska-Szostek, Magdalena Gewartowska, Marek Stanczyk, Beata Narowska, Maria Moscicka-Wesołowska, Waldemar Lech Olszewski   +5 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Uso de esponja cirúrgica para curativo compressivo de enxerto cutâneo Surgical sponge as a pressure dressing for skin grafts

Anais Brasileiros de Dermatologia, 2004
O enxerto cutâneo é um modo efetivo para restaurar feridas. O curativo compressivo é importante para a vitalidade do enxerto. Os autores observaram que o uso de esponja cirúrgica como curativo compressivo em enxertos cutâneos é factível e aconselhável ...
Maurício Zanini, Carlos D' Apparecida Santos Machado Filho, Fábio Timoner   +2 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source