Results 31 to 40 of about 276,615 (314)

Cell-Type-Specific Differentiation and Molecular Profiles in Skin Transplantation: Implication of Medical Approach for Genetic Skin Diseases

Journal of Transplantation, 2011
Skin is highly accessible and valuable organ, which holds promise to accelerate the understanding of future medical innovation in association with skin transplantation, engineering, and wound healing.
Noritaka Oyama, Fumio Kaneko
doaj   +1 more source

Immunology of skin transplantation

Clinics in Dermatology, 2005
Untreated viable allogeneic skin is highly immunogenic. Epidermal Langerhans migrate after transplantation out of the donor skin into the lymph node of the recipient where they can activate T cells capable to mediate rejection. Allogeneic skin is used as a temporary coverage of burn wounds, often in combination with autologous skin grafts.
Richters, C.D., Hoekstra, M.J., du Pont, J.S., Kreis, RW, Kamperdijk, E.W.   +4 more
openaire   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Hair-follicle transplant as chronic skin ulcer treatment

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2022
Chronic skin ulcers treatment is a common challenge in clinical dermatology practice. In recent years, hair-follicles transplantation emerged as an effective chronic skin ulcer treatment.
Leandro Silva, Rui Oliveira Soares
doaj  

Role of customised negative-pressure wound therapy in the integration of split-thickness skin grafts: A randomised control study

Indian Journal of Plastic Surgery, 2017
Background: Split-thickness skin grafting (STSG) is a time-tested technique in wound cover, but many factors lead to suboptimal graft take. Role of custom-made negative-pressure wound therapy (NPWT) is compared with conventional dress in the integration ...
Mir Mohsin, Haroon Rashid Zargar, Adil Hafeez Wani, Mohammad Inam Zaroo, Peerzada Umar Farooq Baba, Sheikh Adil Bashir, Altaf Rasool, Akram Hussain Bijli   +7 more
doaj   +1 more source

An Anhydrous Sodium Chloride Skin Preservation Model for Studies on Keratinocytes Grafting into the Wounds

Pharmaceutics, 2021
Background. Human skin is needed for covering large body areas lost by trauma. The shortcomings of contemporary methods of skin storage are limited preservation time and high immunogenicity if allogeneic. Methods.
Anna Domaszewska-Szostek, Magdalena Gewartowska, Marek Stanczyk, Beata Narowska, Maria Moscicka-Wesołowska, Waldemar Lech Olszewski   +5 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Non‐Cultured Melanocyte‐Keratinocyte Transplantation Combined With NB‐UVB Therapy for Facial Depigmentation Induced by Skin Exfoliator: A Case Report

Clinical Case Reports
Non‐cultured melanocyte‐keratinocyte transplantation combined with narrowband ultraviolet B (NB‐UVB) therapy is a promising and well‐tolerated treatment for facial hypo‐pigmentation following scarring.
Sona Zare, Alireza Jafarzadeh, Maryam Nouri, Solmaz Zare, Mohammad Ali Nilforoushzadeh   +4 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Meek Micrografting Technique for Reconstruction of Extensive Necrotizing Fasciitis of the Anterior Abdomen and Bilateral Femoral Region: A Case Report

Archives of Plastic Surgery, 2023
Necrotizing fasciitis is an uncommon yet fatal soft tissue infection. Current recommended treatment includes antibiotics with repeat surgical exploration and wound debridement followed by reconstruction.
Jyi Cheng Ng, Ahmad Ibrahim Ahmad Zaidi, Jun De Lee, Mohd Faisal Jabar   +3 more
doaj   +1 more source