Results 91 to 100 of about 1,000,962 (278)
PLoS ONE, 2013 Molecular mechanisms leading to pressure ulcer development are scarce in spite of high mortality of patients. Development of pressure ulcers that is initially observed as deep tissue injury is multifactorial.
Olivera Stojadinovic +8 more
doaj +1 more source
Investigating staff knowledge of safeguarding and pressure ulcers in care homes [PDF]
, 2016 Objective: To investigate whether nursing/care home staff regard pressure ulceration as a safeguarding issue; and to explore reporting mechanisms for pressure ulcers in nursing/care homes.
Ousey, K. +7 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu +10 more
wiley +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
Advanced Healthcare Materials, EarlyView.This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Treatment of a Refractory Skin Ulcer Using Punch Graft and Autologous Platelet-Rich Plasma
Case Reports in Dermatological Medicine, 2016 Background. Chronic ulceration of the lower legs is a relatively common condition amongst adults: one that causes pain and social distress and results in considerable healthcare and personal costs.
Mauro Carducci +4 more
doaj +1 more source
Case Reports in Dermatology, 2016 A 50-year-old Japanese woman consulted the emergency department of our hospital for bleeding due to an intractable postoperative wound on the lower abdomen; the postoperative wound was owing to a laparoscopic cholecystectomy performed 1 year previously ...
Keiko Inui +5 more
doaj +1 more source
Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin [PDF]
, 2013 Buruli ulcer (BU), caused by Mycobacterium ulcerans is a chronic necrotizing skin disease. It usually starts with a subcutaneous nodule or plaque containing large clusters of extracellular acid-fast bacilli.
Kwabena Quenin-Fosu +48 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao +10 more
wiley +1 more source
Mycobacterium ulcerans persistence at a village water source of Buruli ulcer patients [PDF]
, 2014 Buruli ulcer (BU), a neglected tropical disease of the skin and subcutaneous tissue, is caused by Mycobacterium ulcerans and is the third most common mycobacterial disease after tuberculosis and leprosy.
Nadia Schürch (383786) +41 more
core +2 more sources
Advanced Materials, EarlyView.Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song +8 more
wiley +1 more source