Development and application of new approaches to study the epidemiology of "mycobacterium ulcerans" disease (Buruli ulcer) in Ghana [PDF]
Mycobacterium ulcerans, causing the devastating skin disease Buruli ulcer (BU), has evolved from the fish pathogen M. marinum. By the acquisition of a virulence plasmid (pMUM) a progenitor of M.
Röltgen, Katharina
core +1 more source
Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa +3 more
wiley +1 more source
Back to basics: biophysical methods in tissue viability research [PDF]
The continued growth of research in the areas of tissue viability and wound care has led to the development of an equally diverse range of techniques to assess wounds and provide some quantitative measure of healing. These range from highly sophisticated
Voegeli, David +3 more
core +1 more source
Risk factors for buruli ulcer: a case control study in Cameroon [PDF]
BACKGROUND: Buruli ulcer is an infectious disease involving the skin, caused by Mycobacterium ulcerans. This disease is associated with areas where the water is slow-flowing or stagnant.
Eyangoh, Sara +29 more
core +2 more sources
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Socio-cultural features of Buruli ulcer and implications for control in Ghana [PDF]
Buruli ulcer (BU) infection, caused by Mycobacterium ulcerans, an environmental pathogen, is a disfiguring disease of the skin and occasionally the bones. Although mortality is rare, morbidity is high.
Ackumey, Mercy
core +1 more source
A survey and comparison of ET-1 level in scleroderma patients with and without pitting ulcer
Introduction: Scleroderma is a systemic disorder with unknown etiology most notably characterized by skin thickening and damage of organs. Endothelin-1(ET-1) plays a role in skin fibrosis.
Mardad Aghaei +7 more
doaj
Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet +11 more
wiley +1 more source
A sero-epidemiological approach to explore transmission of Mycobacterium ulcerans [PDF]
The debilitating skin disease Buruli ulcer (BU) is caused by infection with Mycobacterium ulcerans. While various hypotheses on potential reservoirs and vectors of M. ulcerans exist, the mode of transmission has remained unclear.
Yeboah-Manu, Dorothy +32 more
core +1 more source
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato +27 more
wiley +1 more source

