Results 101 to 110 of about 66,253 (280)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Automatic boomerang attacks search on Rijndael

Journal of Mathematical Cryptology
Boomerang attacks were introduced in 1999 by Wagner (The boomerang attack. In: Knudsen LR, editor. FSE’99. vol. 1636 of LNCS. Heidelberg: Springer; 1999. p.
Rouquette Loïc, Minier Marine, Solnon Christine   +2 more
doaj   +1 more source

Divide-and-Conquer SAT for Exploring Optimal Differential and Linear Characteristics and Its Applications

IACR Transactions on Symmetric Cryptology
Developing automatic search tools to derive optimal characteristics is crucial for both the design and cryptanalysis of symmetric-key primitives.
Kazuma Taka, Kosei Sakamoto, Ryoma Ito, Rentaro Shiba, Shion Utsumi, Takanori Isobe   +5 more
doaj   +1 more source

Matrix Factorization at Scale: a Comparison of Scientific Data Analytics in Spark and C+MPI Using Three Case Studies

, 2016
We explore the trade-offs of performing linear algebra using Apache Spark, compared to traditional C and MPI implementations on HPC platforms. Spark is designed for data analytics on cluster computing platforms with access to local disks and is optimized
Canon, Shane, Chhugani, Jatin, Demmel, James, Devarakonda, Aditya, Gerhardt, Lisa, Gittens, Alex, Harrell, Jim, Kottalam, Jey, Krishnamurthy, Venkat, Liu, Jialin, Mahoney, Michael W., Maschhoff, Kristyn, Prabhat, Racah, Evan, Ringenburg, Michael, Sharma, Pramod, Yang, Jiyan   +16 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Mix-Basis Geometric Approach to Boomerang Distinguishers

IACR Transactions on Symmetric Cryptology
Differential cryptanalysis relies on assumptions like Markov ciphers and hypothesis of stochastic equivalence. The probability of a differential characteristic estimated by classical methods is the key-averaged probability under the two assumptions ...
Chengcheng Chang, Hosein Hadipour, Kai Hu, Muzhou Li, Meiqin Wang   +4 more
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Trail-Estimator: An Automated Verifier for Differential Trails in Block Ciphers

IACR Transactions on Symmetric Cryptology
Differential cryptanalysis is a powerful technique for attacking block ciphers, wherein the Markov cipher assumption and stochastic hypothesis are commonly employed to simplify the search and probability estimation of differential trails. However, these
Thomas Peyrin, Quan Quan Tan, Hongyi Zhang, Chunning Zhou   +3 more
doaj   +1 more source