Results 81 to 90 of about 6,929 (294)
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Impossible Boomerang Attacks Revisited
The impossible boomerang (IB) attack was first introduced by Lu in his doctoral thesis and subsequently published at DCC in 2011. The IB attack is a variant of the impossible differential (ID) attack by incorporating the idea of the boomerang attack. In
Jianing Zhang, Haoyang Wang, Deng Tang
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
skinny wopper n...the captain sat on his bunk and pulled off his "skinny-whopper" boots.PRINTED ITEM DNE-citG.M.Story April 1958Used IUsed IUsed I~ hopper, ~ wapper, -whopper, ~ wop, SKIN ...
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Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
skinny aIt is bad, unfavourable, dangerous.PRINTED ITEM DNE-citG.M.Story April 1962Used IUsed IUsed
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The Skinny on Low-fat and Fat-free Milk and Milk Products
Whether you are young or old, consuming fat-free and low-fat milk products every day is important for good health. This 5-page fact sheet highlights the purpose of including foods from the Milk group in the diet and the daily amounts needed for children ...
Lauren Headrick, Karla P. Shelnutt
doaj +1 more source

