Results 71 to 80 of about 66,253 (280)
Visualizing How Jet Structure Shapes Jet Wakes [PDF]
The ATLAS Collaboration has developed a method to analyze largeradius jets composed of skinny R = 0.2 subjets in heavy-ion collisions. We first demonstrate that the measurements pioneered by ATLAS constrain the value of Lres, the resolution length of QGP—
Kudinoor Arjun +2 more
doaj +1 more source
Compliments, Insults, and the Paradox of Pillow Talk
I haven’t been a skinny girl since I was seven years old. At nine, I was told I wasn’t small enough to sit down and talk to the other girls.
Anonymous,
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Analysis of the Min-Sum Algorithm for Packing and Covering Problems via Linear Programming [PDF]
Message-passing algorithms based on belief-propagation (BP) are successfully used in many applications including decoding error correcting codes and solving constraint satisfaction and inference problems.
Even, Guy, Halabi, Nissim
core
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Cult of Word Fasting [PDF]
This short story replaces the Kickshaws feature for this ...
Morice, Dave
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

