Advanced Science, EarlyView.A multifunctional, 3D porous neural interface combines non‐viral gene delivery and NIR optogenetics to enable minimally invasive, closed‐loop modulation of deep‐brain circuits. Abstract Closed‐loop neuromodulation requires precise, stable, and cell‐specific control of neural circuits with minimal invasiveness.
Chao‐Yi Chu +14 more
wiley +1 more source
Does the type of surgical attire influence surgical site infection rates in intramedullary nailing for proximal femoral fractures? A retrospective analysis. [PDF]
Langenbecks Arch SurgVesseur MAM +7 more
europepmc +1 more source
AI‐Driven Acceleration of Fluorescence Probe Discovery
Advanced Science, EarlyView.We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang +18 more
wiley +1 more source
A Frequency-Dependent and Nonlinear, Time-Explicit Five-Layer Human Head Numerical Model for Realistic Estimation of Focused Acoustic Transmission Through the Human Skull for Noninvasive High-Intensity and High-Frequency Transcranial Ultrasound Stimulation: An Application to Neurological and Psychiatric Disorders. [PDF]
Bioengineering (Basel)Sharma S, Fernandes NATC, Carvalho Ó.
europepmc +1 more source
Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis [PDF]
, 2008 Gerard J. Oakley +2 more
openalex +1 more source
Advanced Science, EarlyView.This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen +8 more
wiley +1 more source
The impact of off-centered positioning on cone beam CT image quality for image-guided brain SRS treatment. [PDF]
J Appl Clin Med PhysMail N, Li F, Lalonde R, Huq MS.
europepmc +1 more source
Mouse models and the evolutionary developmental biology of the skull [PDF]
, 2008 Benedikt Hallgrímsson +1 more
openalex +1 more source
Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes
Advanced Science, EarlyView.In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu +13 more
wiley +1 more source