Results 131 to 140 of about 4,334,492 (252)

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

A Gap Analysis of Deep Brain Stimulation for Childhood‐Onset Movement Disorders

Movement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) is an established and increasingly utilized therapy for childhood‐onset movement disorders. However, pediatric DBS poses unique challenges that are not adequately addressed by adult‐derived paradigms. Objective To identify key gaps in the current use of DBS in childhood‐onset movement disorders and to ...
Daniela Munoz‐Chesta, Carolina Gorodetsky, Todd M. Herrington, Angela L. Hewitt, Daniel E. Lumsden, Jennifer O'Malley, Terence Sanger   +6 more
wiley   +1 more source

Mesenchymal stem cells as cellular factories for targeted P2X7 blockade after traumatic brain injury

Neuroprotection, EarlyView.
This manuscript presents a novel therapeutic strategy using mesenchymal stem cells (MSCs) engineered as living drug factories to deliver a P2X7‐blocking nanobody for treatment of ischemic stroke. By combining targeted cellular delivery with sustained local immunomodulation, the approach aims to overcome key limitations of systemic biologic ...
Lucia Fadon‐Padilla, Chengyan Chu, Lorissa McDougall, Yajie Liang, Chinmoy Sarkar, Marta Lipinski, Tim Magnus, Miroslaw Janowski, Piotr Walczak   +8 more
wiley   +1 more source

A Possible Case of Temporomandibular Joint Dislocation, Trepanation, and Metabolic Bone Disease in a Young Adolescent From North‐Central Myanmar (1000–700 bce)

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT This osteobiography explores the life history of an adolescent who lived during the early‐mid Bronze Age (c. 1000–700 bce) and was buried at Nyaung'gan, a site in north‐central Myanmar. Burial 3b had multiple skeletal lesions, and their bones were covered in well‐remodeled subperiosteal new bone.
Anna Willis, Baptiste Pradier, Thu Thu Win, T. O. Pryce   +3 more
wiley   +1 more source

Middle-Term Follow-Up Outcomes of the Customised Temporomandibular Joint-Skull Base Combined Prosthesis by 3D Printing

International Dental Journal
Introduction: The combined lesions of the temporomandibular joint (TMJ) and skull base pose a considerable clinical challenge, frequently necessitating complex reconstructive procedures, yet established treatment protocols remain insufficient.
Qingyu Xu, Yuxin Zhang, Xiang Wei, Liang Huo, Zixiang Han, Lingtong Bu, Minjie Chen, Jisi Zheng, Chi Yang   +8 more
doaj   +1 more source

Exploring the causes and impact of pediatric complicated mild traumatic brain injuries

PM&R, EarlyView.
Abstract Background Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in children, with mild TBI (mTBI) accounting for approximately 80% of cases. Complicated mTBI (c‐mTBI) is characterized by radiographic evidence of intracranial abnormalities and/or skull fractures.
Andrew D. Kramer, Arianna B. Lanpher, Matthew Mervis, Madison Koval, Zachary Jager, Masaru Teramoto, Michael M. Green   +6 more
wiley   +1 more source

Craniofacial Fracture with Superior Orbital Fissure Syndrome Resulting in Pupil-sparing Oculomotor Nerve Palsy

Plastic and Reconstructive Surgery, Global Open
Summary:. Superior orbital fissure syndrome (SOFS) is a rare complication of craniofacial fracture, caused by damage to cranial nerves Ⅲ, Ⅳ, Ⅴ, and Ⅵ, which typically is associated with ophthalmoplegia, blepharoptosis, pupil dilatation and fixation, and ...
Hiroshi Taniguchi, MD, Hiroshi Nishioka, MD, PhD, Erika Kuriyama, MD, PhD, Yoshikazu Inoue, MD, PhD, Takayuki Okumoto, MD, PhD   +4 more
doaj   +1 more source

Reconstructive aspects in anterior skull base surgery

, 2009
The treatment of malignancies of the anterior skull base is a coordinated multi-specialty approach that combines neurosurgery, otorhinolaryngology and oral and maxillofacial surgery.
Neukam, FW, Nkenke, E, Fenner, M
core   +1 more source

Causes, treatment and outcome of external ear canal tears and avulsions in cats and dogs: 24 cases (2008‒2024)

Veterinary Record, EarlyView.
Abstract Background This study aimed to evaluate the causes, treatment options and associated complications of ear canal tears and avulsions in dogs and cats. Methods This retrospective clinical study includes 14 cats and 10 dogs diagnosed with external ear canal tears and avulsions using otoscopy and/or computed tomography.
Eva M. Billau, Cetina Thiel
wiley   +1 more source

The Relationship of Signs and Symptoms and Complications of Skull Base Fractures with Skull Base CT Scan Findings [PDF]

Background: Skull base fracture is diagnosed with high accuracy by skull base CT scan, but sometimes, due to the patient's general condition, CT scan cannot be performed. The aim of this study was to investigate the predictive value of signs and symptoms
Mehrab Mohammadi, Resident of Neurosurgery, Department of Neurosurgery, Afzalipour, Ali Ebrahimi Nejad, Associate Professor, Neuroscience Research Center, Kerman Univer   +1 more
core