Results 131 to 140 of about 4,468,959 (304)

Directional Deep Brain Stimulation for Parkinson's Disease: Results of an International Crossover Study With Randomized, Double‐Blind Primary Endpoint

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective Published reports on directional deep brain stimulation (DBS) have been limited to small, single‐center investigations. Therapeutic window (TW) is used to describe the range of stimulation amplitudes achieving symptom relief without side effects.
Alfons Schnitzler, Pablo Mir, Matthew A. Brodsky, Leonard Verhagen, Sergiu Groppa, Ramiro Alvarez, Andrew Evans, Marta Blazquez, Sean Nagel, Julie G. Pilitsis, Monika Pötter‐Nerger, Winona Tse, Leonardo Almeida, Nestor Tomycz, Joohi Jimenez‐Shahed, Witold Libionka, Fatima Carrillo, Christian J. Hartmann, Stefan Jun Groiss, Martin Glaser, Florence Defresne, Edward Karst, Binith Cheeran, Jan Vesper, for the PROGRESS Study Investigators   +24 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Selective reconstructive options for the anterior skull base

, 2005
Carcinomas of the ethmoid, frontal, or maxillary sinuses sometimes invade the anterior skull base. It is necessary to perform en-bloc resection for this invasive carcinoma according to the concepts of surgical treatment for head and neck cancer.
KATO, Takashi, NAMEKI, Hideo, NAMEKI, Ichirota   +2 more
core  

A Gap Analysis of Deep Brain Stimulation for Childhood‐Onset Movement Disorders

Movement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) is an established and increasingly utilized therapy for childhood‐onset movement disorders. However, pediatric DBS poses unique challenges that are not adequately addressed by adult‐derived paradigms. Objective To identify key gaps in the current use of DBS in childhood‐onset movement disorders and to ...
Daniela Munoz‐Chesta, Carolina Gorodetsky, Todd M. Herrington, Angela L. Hewitt, Daniel E. Lumsden, Jennifer O'Malley, Terence Sanger   +6 more
wiley   +1 more source

Reconstruction of Anterior Skull Base After Cleaver Trauma: Combined Use of Fascia Lata and Middle Turbinate Flap in a Patient with Concha Bullosa

Turkish Archives of Otorhinolaryngology
This video article presents a 47-year-old male patient who presented to the emergency department after a cleaver bounced off the grinding wheel and lodged between his eyebrows. The patient complained of clear nasal drainage since the trauma.
Serdar Mete, Mustafa Cenk Ecevit
doaj   +1 more source

Frequency and pattern of skull base and vault fracture in isolated head trauma [PDF]

Purpose: In the literature, the number of studies on cases of injury due to isolated head trauma is limited. In addition, there are very few studies and publications on skull base and vault fractures in the forensic literature.
Altunyuva, O., Altunyuva, O\u11fuz, \u130nan\u131r, Nursel T\ufcrkmen, Y\u131lmazlar, Sel\ue7uk, Malc\u131, Emir Bayram, Durak, Dilek, Durak, Vahide Asl\u131han, Fedakar, Recep   +7 more
core   +1 more source

Mesenchymal stem cells as cellular factories for targeted P2X7 blockade after traumatic brain injury

Neuroprotection, EarlyView.
This manuscript presents a novel therapeutic strategy using mesenchymal stem cells (MSCs) engineered as living drug factories to deliver a P2X7‐blocking nanobody for treatment of ischemic stroke. By combining targeted cellular delivery with sustained local immunomodulation, the approach aims to overcome key limitations of systemic biologic ...
Lucia Fadon‐Padilla, Chengyan Chu, Lorissa McDougall, Yajie Liang, Chinmoy Sarkar, Marta Lipinski, Tim Magnus, Miroslaw Janowski, Piotr Walczak   +8 more
wiley   +1 more source

Small Round Blue Cell Tumors with Anterior Skull Base Invasion

, 2013
Objective: To review various small round blue cell tumors (SRBCTs) with anterior skull base invasion and examine surgical technique and survival. Background : SRBCTs are a rare and heterogenous group of poorly differentiated malignant neoplasms that ...
Rudman, Jason, Sargi, Zoukaa, Fundakowski, Christopher   +2 more
core   +1 more source

Application of Photogrammetry and Mesh Comparison in the Study of Human Cranial Morphology

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT Photogrammetric methods for generating three‐dimensional (3D) models are becoming increasingly widespread in the fields of archaeology and biological anthropology. In particular, the study of the variability of skull morphology (generated by the ancestry of the individual or by the application of certain cultural practices) using 3D models is ...
Carlos Cancio Moreno, Javier Lescure, Antonio González‐Martín   +2 more
wiley   +1 more source

Exploring the causes and impact of pediatric complicated mild traumatic brain injuries

PM&R, EarlyView.
Abstract Background Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in children, with mild TBI (mTBI) accounting for approximately 80% of cases. Complicated mTBI (c‐mTBI) is characterized by radiographic evidence of intracranial abnormalities and/or skull fractures.
Andrew D. Kramer, Arianna B. Lanpher, Matthew Mervis, Madison Koval, Zachary Jager, Masaru Teramoto, Michael M. Green   +6 more
wiley   +1 more source