Results 51 to 60 of about 4,468,959 (304)

Skull Base Cholesterol Granuloma: A Distinct Entity?

open access: yes, 2015
Objective: Cholesterol granulomas (CG) are the most common benign lesions of the petrous apex (PA) and have very distinct computed tomography (CT) and magnetic resonance imaging (MRI) characteristics.
Telischi, Fred F   +7 more
core   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

open access: yesAdvanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne   +15 more
wiley   +1 more source

Endoscopic Anterior Hemi-Skull Base Resection and Reconstruction

open access: yes, 2015
Objectives/Hypothesis: This study aims to validate the efficacy endoscopic anterior hemi-skull base resection and reconstruction. Methods: A retrospective review of all patients treated for skull base tumors with an endoscopic anterior hemi-skull base ...
Al-Bar, Mohammad H   +4 more
core   +1 more source

Yoda1‐Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

open access: yesAdvanced Science, EarlyView.
Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng   +16 more
wiley   +1 more source

Skull-base fractures: Pearls of etiopathology, approaches, management, and outcome

open access: yesApollo Medicine, 2019
Fractures involving skull bases usually results from high-velocity impacts, i.e., motor vehicular accidents. The estimated incidence of skull-base fracture varies from 4% of all head injuries to 7%–16% of closed head injuries.
K V. L Narasinga Rao   +6 more
doaj   +1 more source

Age‐Related Lamin B1 Deficiency Activates SLC7A11‐Dependent Disulfidptosis to Impair Osteogenesis via Intercepting Mitochondrial Fission

open access: yesAdvanced Science, EarlyView.
This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu   +12 more
wiley   +1 more source

SURGERY OF ANTERIOR SKULL BASE FOR NEOPLASMS OF PARANASAL SINUSES

open access: yes, 1994
1st International Skull Base Congress -- JUN 14-20, 1992 -- HANNOVER, GERMANY[Abstract Not ...
OZLUOGLU, LN   +3 more
core   +1 more source

Death due to fracture of thin calvarial bones after a fall: A forensic approach

open access: yesChinese Journal of Traumatology, 2017
A 45-year-old male was autopsied. He had fallen backwards from a two-stairs height to the ground and passed away. A skull fracture was detected in the left occipital area, extending up to the left side of the skull base.
Georgios Sioutas   +3 more
doaj   +1 more source

Bilateral External Auditory Canal Cholesteatoma Invading Skull Base [PDF]

open access: yes, 2006
External auditory canal cholesteatoma is an uncommon lesion of the external auditory canal, which usually present with otorrhea and chronic dull pain. It usually eroded bony portion of external auditory canal wall extensively with progressive bony lysis,
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core  

Prenatal Presentation of RMRP‐Related Skeletal Dysplasia: Clinical and Genomic Expansion

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT The RNA subunit of the mitochondrial RNA processing endoribonuclease complex is encoded by RMRP. Biallelic variants in RMRP are known for anauxetic dysplasia 1 (AD), cartilage‐hair hypoplasia (CHH), and metaphyseal dysplasia without hypotrichosis.
Radhakrishnan Periyasamy   +21 more
wiley   +1 more source

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