Lactate Accelerates Early Angiogenesis and Bone Regeneration Through Macrophage M1 Polarisation
During the early stage of bone defect healing, lactate accumulates and contributes to increasing NOD1 expression by stabilising HIF1α that in turn triggers a calcium influx, which ultimately polarises macrophages towards the M1 phenotype and accelerates vascularisation of endothelial cells.
Lulu Liu +10 more
wiley +1 more source
Modern technology complements classic technique: 3D-printed inter-locking cutting guides for frontal sinus osteoma resection and reconstruction with split-calvarial bone graft. [PDF]
Brown CW +6 more
europepmc +1 more source
HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann +7 more
wiley +1 more source
Editorial: Molecular biology and treatment strategies for tumors of middle and inner ear. [PDF]
Rosiak O, Konopka W, Fishman A.
europepmc +1 more source
Brain-specific immune hub activation in paediatric focal lesional epilepsy: a case-control study. [PDF]
Gennari AG +9 more
europepmc +1 more source
Clinical study on skull metastases of malignant neoplasms.
ONDA, Jun +4 more
openaire +1 more source
Perineurioma‐like EMA‐positive calvarial neoplasms: clinicopathological study of eight cases
Perineurioma‐like, EMA‐positive calvarial neoplasms (PLECN) are a rare group of intraosseous spindle cell tumours that demonstrate overlapping morphologic features of perineurioma and fibroblastic meningioma. These lesions tend to behave indolently but show a propensity for progressive growth.
Raheel Rizwan +9 more
wiley +1 more source
Nasopharyngeal carcinoma masquerading as a primary sinonasal mass: a case report. [PDF]
Lahiri A, Roy N.
europepmc +1 more source
Abstract Brain surgery is a widely practised and effective treatment for brain tumours, but accurately identifying and classifying tumour boundaries is crucial to maximise resection and avoid neurological complications. This precision in classification is essential for guiding surgical decisions and subsequent treatment planning.
Neetu Sigger +2 more
wiley +1 more source
Anlotinib-temozolomide combination achieves durable response in multimodal-resistant primary breast angiosarcoma with skull base metastasis and dural involvement: a case report. [PDF]
Song S, Chen W, Li X, Zhang Y, Wang Y.
europepmc +1 more source

