Results 71 to 80 of about 475,529 (364)

The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]

, 2020
Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J, Kato, Shumei, Kurzrock, Razelle, Lippman, Scott M   +3 more
core  

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, In collaboration with the Consensus Expert Panel (CEP) members   +19 more
wiley   +1 more source

Proptosis secondary to a solitary plasmacytoma of the sphenoid bone: a case report on a rare skull base tumour

Egyptian Journal of Neurosurgery, 2022
Background Plasmacytomas of the skull base are not commonly encountered in clinical practice, with few reported cases in the literature. They form part of the spectrum of plasma cell neoplasms and are classified as a solitary bone plasmacytoma if arising
Panduranga Seetahal-Maraj, Patrick Knight, Narindra Ramnarine   +2 more
doaj   +1 more source

Monocular visual loss in a disseminated colorectal malignancy—A case report of a rare skull base metastasis

Radiology Case Reports, 2023
Neoplasms of the orbit may be primary, secondary (infiltration from the adjacent structures), or metastatic (from distant structures). It can be divided into 3 histologic categories: benign, benign but locally aggressive, and malignant.
Ahmed T. Abdelhamid, MBChB, Tarek A. Khater, MBChB   +1 more
doaj   +1 more source

Endoscopic nasal versus open approach for the management of sinonasal adenocarcinoma: a pooled-analysis of 1826 patients [PDF]

, 2015
Surgical resection represents the gold standard for the treatment of sinonasal malignancies. This study reviewed the published outcomes on endoscopic surgery or endoscopic-assisted surgery versus open approach for the management of sinonasal ...
Choussy Olivier, De Raucourt Dominique, Deganello Alberto, Gallo Oreste, Georgalas Christos, Meccariello Giuseppe, Vitali Daniele   +6 more
core   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

TUMORS OF THE NOSE AND PARANASAL SINUSES IN CHILDREN, CLINICAL OBSERVATIONS

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2020
Resume. Neoplasms of the nasal cavity and perinasal sinuses at the beginning of their development are asymptomatic or non-specific symptoms may appear that mask them as inflammatory diseases (acute and chronic rhinosinusitis).
Rakova S. N., Halavach K. N., Logis O. V., Borodavko P. N., Bobrishev A. I.   +4 more
doaj   +1 more source

Rhabdomyosarcoma of the skull with EWSR1 fusion and ALK and cytokeratin expression: a case report

Journal of Pathology and Translational Medicine
Rhabdomyosarcoma (RMS) comprises of heterogeneous group of neoplasms that occasionally express epithelial markers on immunohistochemistry (IHC). We herein report the case of a patient who developed RMS of the skull with EWSR1 fusion and anaplastic ...
Hyeong Rok An, Kyung-Ja Cho, Sang Woo Song, Ji Eun Park, Joon Seon Song   +4 more
semanticscholar   +1 more source

A case report and genetic characterization of a massive acinic cell carcinoma of the parotid with delayed distant metastases. [PDF]

, 2013
We describe the presentation, management, and clinical outcome of a massive acinic cell carcinoma of the parotid gland. The primary tumor and blood underwent exome sequencing which revealed deletions in CDKN2A as well as PPP1R13B, which induces p53.
Agrawal, Sumit K, Barrett, John W, Boutros, Paul C, Chan-Seng-Yue, Michelle, Dowthwaite, Samuel A, Fung, Kevin, Harding, Nicholas J, Koropatnick, James, Lambin, Philippe, Macneil, S Danielle, Mymryk, Joe S, Nichols, Anthony C, Palma, David A, Starmans, Maud HW, Waggott, Daryl, Wehrli, Bret, Winquist, Eric, Yoo, John   +17 more
core   +3 more sources

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source