Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
A STUDY OF INDONESIAN SLANG IN TWO LUPUS MOVIES [PDF]
This study aims to investigate the Indonesian Slang used in the two Indonesian movies, entitled Lupus and to reveal the commonalities and differences of Slang usage in the different time slot movies. The data are the spoken slang in the two movies; Lupus:
Marwa, Annisa Friski
core
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Relationship between Gender and Learning of American Slang by Iranian EFL Students: A Study following Kolb’s Learning Styles Model [PDF]
One of the most significant current discussions in learning and teaching communicative methods, especially in informal and communicative language, is the teaching and learning of American slang.
Mariam Biabani , Siros Izadpanah
doaj
Three Approaches of Word Sentence Meaning in Translation of English Slang Word Into Indonesian in the Novel “the Adventure of Oliver Twist” [PDF]
The slang expression means coming to democratic atmosphere in language since the meaning embodied is not absolute. It depends upon who uses it, in which group the users belong to, and in what situation slang word occur.
Sunny, N. P. (Ni)
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Penggunaan Slang Words (Gaya Bahasa Slang) Melalui Aplikasi Tik Tok di Kalangan Mahasiswa
The rapid development of technology information affects the culture of society. Social media as a product of today's development has become a necessity. The need for social media has an impact on the need for la nguage which has led to the development of
Dede Tresna Wiyanti +4 more
doaj +1 more source
AN ANALYSIS OF SLANG LANGUAGE USED BY LIM JUGYEONG AS “PRETTY GIRL” IN YAONGYI ENGLISH VERSION WEBTOON “TRUE BEAUTY” [PDF]
The use of slang, popularly used in conversation, is generally used in casual conversation. Slang is not just utilized in direct conversation, it is also quite entertaining to employ on online platforms, such as character conversations in webtoons.
Akhmad, Salsabilla Jauharah
core

