Results 81 to 90 of about 119,195 (300)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A Comparative Analysis of General Slang in the Macrosystem of Sub-Standard English

RUDN Journal of Language Studies, Semiotics and Semantics, 2016
The purpose of this article is to define the lexical and semantic meaning of common and special slang through practical and theoretical knowledge. In the research process the author has used an extensive scientific literature of domestic and foreign ...
A N Gamov
doaj  

PENGGUNAAN BAHASA PROKEM WARIA DI KOTA TRENGGALEK [PDF]

, 2007
Language is a tool of social interaction or a tool of human communication. In any activity, language can provide information in the form of thoughts, ideas, intentions, or feelings directly.
Sundari, Sundari
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

The Use of Slang Words Among Junior High School Students in Everyday Conversation (a Case Study in the Ninth Grade Students of a Junior High School in Bandung) [PDF]

, 2013
The study is entitled "The Use of Slang Words among Junior High School Students in Everyday Conversation." It aims to investigate slang words used by the ninth grade students.
Pradianti, W. (Widya)
core  

Expressive devices in the language of English- and Spanish-speaking youth [PDF]

, 2011
The aim of this paper is threefold: first, to introduce the topic of youth slang by giving an overview of its main characteristics; second, to show the different word-formation processes that slang has to make the speaker’s message more expressive; and ...
Rodríguez González, Félix, Stenström, Anna-Brita   +1 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Лексико семантична роль сленгу у мовленні молоді (на основі творчості американської співачки нікі мінаж) (Lexico-semantic role of slang in the (-the) youth communication (based on the works of the American singer Nicki Minaj) [PDF]

, 2017
У тезах розглянуто сленг у творчості американської спі- вачки Нікі Мінаж (2007–2017), проаналізовано особливості вживання, виділено семантичні групи сленгу відповідно до різних категорій та досліджено його роль у житті сучасно- го суспільства.
Бебко, І. (I. Bebko)
core