Results 61 to 70 of about 19,081 (291)
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
This article deals with the study of the features of the youth slang using in modern English language. The aim of the article is to analyse the usage of slang expressions among young generation.
Habibullayeva Mavludaxon Umarjon qizi +2 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Generating a contract checker for an SLA language [PDF]
SLAng is a language for expressing Service LevelAgreements (SLAs) under development as part of the Europeanproject TAPAS. It is defined using a meta-model, an instance ofthe Meta-Object Facility (MOF) model, in which the relationshipbetween the syntax of
Skene, J, Emmerich, W
core
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Tradução de gírias em Harry Potter: um estudo com base em corpus [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Estudos da Tradução, Florianópolis, 2014.Este estudo abarca a intersecção dos Estudos da Tradução com a Literatura Infantojuvenil ...
Santos, Caroline Reis Vieira
core
YOUTH SLANG: TRANSLATION ASPECT [PDF]
his article is devoted to the analysis of the specific features and ways of translating youth slang from English into Ukrainian. The author clarifies the concept of slang. The difficulties of translation of slang are described. The methods of translating
Клименко, А.
core
Youth and student slang in British and American English: an annotated bibliography
This article contains an annotated bibliography of the slang used by young people, and specifically the slang of students, in both Britain and the United States. In addition, there is a brief account of the English influences on foreign youth slang. Some
Rodríguez González, Félix
core +1 more source

