Results 81 to 90 of about 118,368 (283)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Лексико семантична роль сленгу у мовленні молоді (на основі творчості американської співачки нікі мінаж) (Lexico-semantic role of slang in the (-the) youth communication (based on the works of the American singer Nicki Minaj) [PDF]

open access: yes, 2017
У тезах розглянуто сленг у творчості американської спі- вачки Нікі Мінаж (2007–2017), проаналізовано особливості вживання, виділено семантичні групи сленгу відповідно до різних категорій та досліджено його роль у житті сучасно- го суспільства.
Бебко, І. (I. Bebko)
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Comparative Analysis of General Slang in the Macrosystem of Sub-Standard English

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2016
The purpose of this article is to define the lexical and semantic meaning of common and special slang through practical and theoretical knowledge. In the research process the author has used an extensive scientific literature of domestic and foreign ...
A N Gamov
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Brit Wit: A Slang Quiz [PDF]

open access: yes, 1987
The wit and wisdom of the common people are preserved in slang words and phrases which can sometimes be a little baffling or require insider knowledge, as when a Cockney says, I wouldn\u27t like to be a pawnbroker\u27s sign on a night like this.
Ashley, Leonard R. N.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

THE COMPARISON OF SLANG TRANSLATION STRATEGIES USED BY THE ENGLISH MAJOR AND NON ENGLISH MAJOR TRANSLATORS IN THE SUBTITILE OF THE HANGOVER FILM [PDF]

open access: yes, 2015
: This paper was aimed at analyzing and comparing the slang translation strategies employed by the English major and non English major translators in the subtitle of The Hangover film and finding out the slang translation quality.
Islami, Hasya Nur
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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