Results 91 to 100 of about 3,033 (181)

Proteomic Changes Associated With Endogenous FBXW7 Mutations in Moderately Differentiated Endometrial Cancer Cells Include Increased TROP2 and Galectin‐3 Levels

open access: yesCancer Medicine, Volume 14, Issue 6, March 2025.
ABSTRACT Background Endometrial cancer (EC) is the fourth most commonly diagnosed cancer among women in the US and the fifth leading cause of cancer death in this population. The FBXW7 tumor suppressor gene is frequently mutated in all molecular subtypes of EC.
Mary Ellen Urick   +3 more
wiley   +1 more source

Identification of chromosomal rearrangements in colorectal cancer [PDF]

open access: yes, 2015
Curs 2014-2015Cancer research is continuously shedding light into these worldwide leading diseases. It is mandatory to have higher knowledge in cancer biology to consequently find out new candidate biomarkers and therapeutics.
Moratalla Navarro, Ferran
core  

Endometriosis : involvement of stem cells and clinical impact [PDF]

open access: yes, 2016
Introduction: Endometriosis is a common gynaecological disease affecting up to 10% of women of reproductive age. The women suffer from severe abdominal pain and infertility as a consequence of the chronic inflammation.
Andersson Di Claudio, Karin
core   +1 more source

A Unique Signature for Cancer‐Associated Fibroblasts in Melanoma Metastases

open access: yesPigment Cell &Melanoma Research, Volume 38, Issue 2, March 2025.
In this study, we analyzed the transcriptional signatures of CAFs and normal fibroblasts from murine melanoma primary tumors and corresponding melanoma lung metastases. Single‐cell analysis revealed distinct clusters for primary tumor and metastasis CAFs. In lung metastases Saa3 expression is a hallmark of metastasis CAFs.
Saskia Tauch   +12 more
wiley   +1 more source

Evaluation of Egg Quality Differences Between Indigenous, Synthetic, and Exotic Chickens Under the Same Management

open access: yesJournal of Food Processing and Preservation, Volume 2025, Issue 1, 2025.
Egg quality is a critical factor influencing consumer preference, nutrition, and industrial utilization, yet comparative evaluations of indigenous, synthetic, and exotic chicken breeds under uniform management are limited. This study assessed the physical, functional, and nutritional properties of eggs from Horro and Jarso (indigenous), White Feather ...
Dejenie Mengistie   +7 more
wiley   +1 more source

Current role of cytopathology in the molecular and computational era: The perspective of young pathologists

open access: yesCancer Cytopathology, Volume 132, Issue 11, Page 678-685, November 2024.
Abstract Cytopathology represents a well established diagnostic approach because of its limited cost, reliability, and minimal invasiveness with respect to other methodologies. The evolving complexity of the different classifications systems and the implementation of ancillary techniques to refine the diagnosis is progressively helping in the risk of ...
Alessandro Caputo   +2 more
wiley   +1 more source

Renal phosphaturia during metabolic acidosis revisited: molecular mechanisms for decreased renal phosphate reabsorption [PDF]

open access: yes, 2018
During metabolic acidosis (MA), urinary phosphate excretion increases and contributes to acid removal. Two Na+-dependent phosphate transporters, NaPi-IIa (Slc34a1) and NaPi-IIc (Slc34a3), are located in the brush border membrane (BBM) of the proximal ...
Biber, Jürg   +7 more
core  

Unveiling Varied Cell Death Patterns in Lung Adenocarcinoma Prognosis and Immunotherapy Based on Single‐Cell Analysis and Machine Learning

open access: yesJournal of Cellular and Molecular Medicine, Volume 28, Issue 22, November 2024.
ABSTRACT Programmed cell death (PCD) pathways hold significant influence in the etiology and progression of a variety of cancer forms, particularly offering promising prognostic markers and clues to drug sensitivity for lung adenocarcinoma (LUAD) patients.
Zipei Song   +10 more
wiley   +1 more source

Going beyond EGFR [PDF]

open access: yes, 2017
a substantial proportion of non-small-cell lung cancer (NSCLC), and adenocarcinoma in particular, depends on a so-called ‘driver mutation' for their malignant phenotype.
Peters, S., Zimmermann, S.
core  

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