Results 21 to 30 of about 3,033 (181)

The sodium-phosphate co-transporter SLC34A2, and pulmonary alveolar microlithiasis: Presentation of an inbred family and a novel truncating mutation in exon 3

Respiratory Medicine Case Reports, 2015
Pulmonary alveolar microlithiasis is a disorder in which many tiny fragments (microliths) of calcium phosphate gradually accumulate in alveoli. Loss of function mutations in the gene SLC34A2 coding for the sodium phosphate co-transporter (NaPi-IIb) are ...
Marco Favio Michele Vismara, Emma Colao, Fernanda Fabiani, Francesco Bombardiere, Oscar Tamburrini, Caterina Alessio, Francesco Manti, Gerolamo Pelaia, Pasquale Romeo, Rodolfo Iuliano, Nicola Perrotti   +10 more
doaj   +2 more sources

Pulmonary alveolar microlithiasis: A case report and brief review of literature [PDF]

Caspian Journal of Internal Medicine
Background: Pulmonary alveolar microlithiasis (PAM), a rare autosomal recessive pulmonary disease, is mainly characterized by extensive calcium phosphate microliths deposition in the alveoli. The major mutation, causing the characteristic of this disease,
Reza Mohseni Ahangar, Mohammad Golparvar azizi, Sara Babazadeh, Seyed Ali akbar Hosseini nasab, Ali Tavakoli Pirzaman   +4 more
doaj   +1 more source

Partial renal deletion of Klotho is not sufficient to impact renal electrolyte handling in distal convoluted tubule specific knock‐out mice

Physiological Reports
Klotho controls renal electrolyte handling by modulating tubular reabsorption of calcium and phosphate through the epithelial calcium channel TRPV5 and sodium phosphate co‐transporter NPT2A.
Teodora V. Grigore, Quinty M. Leusink, Malou Zuidscherwoude, Caro Bos, Hannes Olauson, Joost Hoenderop   +5 more
doaj   +2 more sources

Non-Small Cell Lung Cancer Testing on Reference Specimens: An Italian Multicenter Experience. [PDF]

Oncol Ther
Introduction: Biomarker testing is mandatory for the clinical management of patients with advanced non-small cell lung cancer (NSCLC). Myriads of technical platforms are now available for biomarker analysis with differences in terms of multiplexing ...
Pepe F, Russo G, Venuta A, Scimone C, Nacchio M, Pisapia P, Goteri G, Barbisan F, Chiappetta C, Pernazza A, Campagna D, Giordano M, Perrone G, Sabarese G, Altimari A, de Biase D, Tallini G, Calistri D, Chiadini E, Capelli L, Santinelli A, Gulini AE, Pierpaoli E, Badiali M, Murru S, Murgia R, Guerini Rocco E, Venetis K, Fusco N, Morotti D, Gianatti A, Furlan D, Rossi G, Melocchi L, Russo M, De Luca C, Palumbo L, Simonelli S, Maffè A, Francia di Celle P, Venesio T, Scatolini M, Grosso E, Orecchia S, Fassan M, Balistreri M, Zulato E, Reghellin D, Lazzari E, Santacatterina M, Piredda ML, Riccardi M, Laurino L, Roz E, Longo D, Romeo DP, Fazzari C, Moreno-Manuel A, Puglia GD, Prjibelski AD, Shafranskaya D, Righi L, Listì A, Vitale D, Iaccarino A, Malapelle U, Troncone G.   +66 more
europepmc   +4 more sources

SLC34A2 inhibits tumorigenesis and progression via upregulating LRRK2/TTF-1/SELENBP1 axis in lung adenocarcinoma. [PDF]

Cancer Gene Ther
Zhu Y, An N, Zhang Q, Liu Y, Gu P, Zhao J, Pan W, Pu Q, Wen Z.   +8 more
europepmc   +3 more sources

Simultaneous detection of lung fusions using a multiplex RT-PCR next generation sequencing-based approach:A multi-institutional research study [PDF]

, 2018
Contains fulltext : 195300.pdf (publisher's version ) (Open ...
A Marchetti, A Uguen, A Vaishnavi, AK Virmani, Aldo Scarpa, Alexander Boag, Andrea Mafficini, Anna Maria Rachiglio, Anne Reiman, Astrid Hirschmann, Bastiaan Tops, Cancer Genome Atlas Research N, Cecily P. Vaughn, D Matsubara, Delphine Le Corre, E Ardini, F Li, Federica Zito Marino, Harriet E. Feilotter, Henriette M. Kurth, Hélène Blons, Ian A. Cree, JF Gainor, José Carlos Machado, José Luis Costa, JP Koivunen, K Rikova, K Takeuchi, Kazuko Sakai, Kazuto Nishio, KD Davies, Kelli Bramlett, KF To, L Ding, L Tembuyser, LM Sholl, M Soda, Marjolijn J. L. Ligtenberg, ME Lira, Michel Bihl, ML Wallander, N Pfarr, Nicola Normanno, Orla Sheils, Pierre Laurent-Puig, RM Phelps, Rosella Petraroli, Roy R. L. Bastien, S Scarpino, SM Ali, Susan Crocker, T Kohno, Varun Bagai, X Gao, Y Pan, Z Dai   +55 more
core   +9 more sources

Recognition of the sodium-dependent phosphate transporter NaPi2b by monoclonal antibodies N-NaPi2b in ovarian cancer cells

Учёные записки Казанского университета: Серия Естественные науки, 2020
The sodium-dependent phosphate cotransporter NaPi2b encoded by the SLC34A2 gene is a transmembrane protein that belongs to the family of phosphate transporters SLC34 and is involved in maintaining phosphate homeostasis in the human body.
L.F. Minigulova, V.S. Skripova, A.K. Nurgalieva, D.V. Savenkova, A.S. Kozlova, N.I. Akberova, D.D. Reshetnikova, L.A. Savinska, O.M. Garifulin, M.V. Bogdanov, R.G. Kiyamova   +10 more
doaj   +1 more source

Sodium-dependent phosphate transporter NaPi2b as a potential predictive marker for targeted therapy of ovarian cancer

Biochemistry and Biophysics Reports, 2021
The high mortality rate from ovarian cancer is due to the asymptomatic nature of the course of the disease, which leads to the diagnosis of ovarian cancer in later stages.
A.K. Nurgalieva, V.E. Popov, V.S. Skripova, L.F. Bulatova, D.V. Savenkova, R.A. Vlasenkova, S.Z. Safina, E. Zh Shakirova, V.V. Filonenko, M.V. Bogdanov, R.G. Kiyamova   +10 more
doaj   +1 more source

A rare case of pulmonary alveolar microlithiasis [PDF]

, 2015
A 47-year-old asymptomatic man with no significant family history was referred to our faculty because of an abnormal chest X-ray (CXR). The CXR, similar to his CXR 10 years previously, showed bilaterally increased interstitial markings suggestive of
Asciak, Rachelle, Mizzi, Adrian, Montefort, Stephen, Pullicino, Richard   +3 more
core   +1 more source

The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation [PDF]

, 2012
Patients with lung cancer often present with metastatic disease and therefore have a very poor prognosis. The recent discovery of several novel ROS receptor tyrosine kinase molecular alterations in non–small cell lung cancer (NSCLC) presents a ...
Bronson, Roderick T., Charest, Alain, de Feraudy, Sebastien, Johnson, Hannah, Jun, Hyun Jung, White, Forest M.   +5 more
core   +2 more sources