Dr. Jekyll and Mr. Hyde: MAP17’s up-regulation, a crosspoint in cancer and inflammatory diseases [PDF]
Inflammation is a common defensive response that is activated after different harmful stimuli. This chronic, or pathological, inflammation is also one of the causes of neoplastic transformation and cancer development. MAP17 is a small protein localized
Carnero Moya, Amancio +1 more
core +1 more source
miR-199a-3p and miR-214-3p improve the overall survival prediction of muscle- invasive bladder cancer patients after radical cystectomy [PDF]
To improve the clinical decision-making regarding further treatment management and follow-up scheduling for patients with muscle-invasive bladder cancer (MIBC) after radical cystectomy (RC), a better prediction accuracy of prognosis for these patients is
Buckendahl, Laura +7 more
core +1 more source
High expression of SLC34A2 is a favorable prognostic marker in lung adenocarcinoma patients
Dysregulation of SLC34A2 (NaPi2b) in tumors has attracted wide attention, but its expression and function in non–small cell lung cancer remains unclear.
Zhaoxuan Zhang +6 more
doaj +1 more source
Pulmonary alveolar microlithiasis: A report of two unique cases
Pulmonary alveolar microlithiasis (PAM) is an inherited autosomal recessive disease. PAM is classically characterized by calcium phosphate deposition within alveolar airspaces due to SLC34A2 (solute carrier family 34 member 2) gene mutation located on ...
Haneen Al-Maghrabi +3 more
doaj +1 more source
Targeting NaPi2b in ovarian cancer. [PDF]
Novel biomarkers are needed to direct new treatments for ovarian cancer, a disease for which the standard of care remains heavily focused on platinum-based chemotherapy.
Banerjee, S +3 more
core +3 more sources
Cancer-associated chromosomal translocations are reported to generate oncogenic circular RNA (circRNA), contributing to tumorigenesis. The fusion gene SLC34A2-ROS1 (solute carrier family 34 member 2 and ROS proto-oncogene 1) plays an important role in ...
Ke Wu +9 more
doaj +1 more source
Pulmonary Alveolar Microlithiasis: A Unique Case of Familial PAM Complicated by Transplant Rejection
Background. Pulmonary alveolar microlithiasis (PAM) is a rare lung disease characterized by the deposition of calcium phosphate microliths or calcospherites, within the alveolar airspace.
Austin Helmink +2 more
doaj +1 more source
Fine Mapping QTLs Affecting Milk Production Traits on BTA6 in Chinese Holstein with SNP Markers
Our previous studies demonstrated that the region around markers BMS470 and BMS1242 on BTA6 showed a linkage to 305-d milk yield and composition traits in the Chinese Holstein population.
Rui LIU +8 more
doaj +1 more source
A Catalog of 5’ Fusion Partners in ROS1-Positive NSCLC Circa 2020
ROS1 fusion–positive (ROS1+) NSCLC was discovered in 2007, the same year as the discovery of ALK-positive (ALK+) NSCLC but has trailed ALK+ NSCLC in terms of development.
Sai-Hong Ignatius Ou, MD PhD +1 more
doaj +1 more source
Molecular Genetic Characterization of Individual Cancer Cells Isolated via Single-Cell Printing. [PDF]
Intratumoral genetic heterogeneity may impact disease outcome. Gold standard for dissecting clonal heterogeneity are single-cell analyses. Here, we present an efficient workflow based on an advanced Single-Cell Printer (SCP) device for the study of gene ...
Julian Riba +14 more
doaj +1 more source

