Results 71 to 80 of about 2,265 (159)

Diffuse pulmonary ossification: A case report unveiling clinical and histopathological challenges

open access: yesRespiratory Medicine Case Reports, 2023
Diffuse pulmonary ossification (DPO) is a rare pulmonary condition characterized by the diffuse formation of mature bone in the lungs. Pulmonary ossification, in general, can be subdivided into diffuse pulmonary ossification (DPO) and nodular pulmonary ...
Francesca Polit   +9 more
doaj   +1 more source

Sodium-dependent phosphate transporter NaPi2b as a candidate for targeted therapy: features of structure, function, and expression

open access: yesУспехи молекулярной онкологии
The sodium-dependent phosphate transporter NaPi2b is an integral membrane protein of the SLC34 phosphate transporter family and is an attractive target for precision therapy of several human diseases.
R. G. Kiyamova   +2 more
doaj   +1 more source

Development of an in vitro model to study the role of disulfide bonds in the largest extracellular domain of the sodium-dependent phosphate transporter NaPi2b in OVCAR-8 ovarian carcinoma cells

open access: yesУспехи молекулярной онкологии
Introduction. The sodium-dependent phosphate transporter NaPi2b is a promising target for targeted antitumor therapy. There is the largest extracellular domain (ECD) containing a cryptic MX35 epitope, against which therapeutic antibodies have been ...
V. S. Skripova   +5 more
doaj   +1 more source

Modern approaches in suicidal gene therapy of malignant neoplasms

open access: yesУспехи молекулярной онкологии
One of the promising directions in antitumor therapy is suicidal gene therapy based on the introduction of cytotoxic genes into tumor cells. Most often, these genes encode for enzymes of bacterial or viral origin, capable of direct or indirect killing of
E. V. Dudkina   +2 more
doaj   +1 more source

Pulmonary alveolar microlithiasis: two case reports and review of the literature [PDF]

open access: yesEuropean Respiratory Review, 2012
Pulmonary alveolar microlithiasis is a rare diffuse lung disease characterised by deposition of calcium phosphate within the alveolar airspaces. The disease is usually discovered from birth up to 40 yrs of age and is often diagnosed incidentally during ...
Elisabeth Bendstrup   +3 more
doaj  

La microlithiase alvéolaire: à propos d'une nouvelle observation

open access: yesThe Pan African Medical Journal, 2017
La microlithiase alvéolaire (MLA) est une affection rare, caractérisée par l'accumulation de concrétions calciques dans la lumière alvéolaire pulmonaire.
Nahid Zaghba   +3 more
doaj   +1 more source

Pulmonary alveolar microlithiasis: no longer in the stone age

open access: yesERJ Open Research, 2020
Pulmonary alveolar microlithiasis (PAM) is a rare parenchymal lung disease caused by variants in the SCL34A2 gene and characterised by the accumulation of intra-alveolar microliths. PAM has been reported in fewer than 1100 cases throughout the world.
Elisabeth Bendstrup   +1 more
doaj   +1 more source

Pulmonary alveolar microlithiasis

open access: yesLung India, 2013
Pulmonary alveolar microlithiasis (PAM) is a rare, chronic lung disease with bilateral intra-alveolar calcium and phosphate deposition throughout the lung parenchyma with predominance to lower and midzone.
Surender Kashyap, Prasanta R Mohapatra
doaj   +1 more source

Identification of potential novel biomarkers to differentiate malignant thyroid nodules with cytological indeterminate

open access: yesBMC Cancer, 2020
Background The fine-needle aspiration (FNA) biopsy was broadly applied to clinical diagnostics evaluation for thyroid carcinomas nodule, while companioning with higher uncertainty rate (15~30%) to identify malignancy for cytological indeterminate cases ...
Dandan Wu   +4 more
doaj   +1 more source

FAM111A is dispensable for electrolyte homeostasis in mice

open access: yesScientific Reports, 2022
Autosomal dominant mutations in FAM111A are causative for Kenny-Caffey syndrome type 2. Patients with Kenny-Caffey syndrome suffer from severe growth retardation, skeletal dysplasia, hypoparathyroidism, hypocalcaemia, hyperphosphataemia and ...
Barnabas P. Ilenwabor   +7 more
doaj   +1 more source

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