Results 81 to 90 of about 2,265 (159)

Characterization of inorganic phosphate transport in the triple-negative breast cancer cell line, MDA-MB-231. [PDF]

open access: yesPLoS ONE, 2018
Recent studies demonstrate that interstitial inorganic phosphate is significantly elevated in the breast cancer microenvironment as compared to normal tissue.
Thais Russo-Abrahão   +9 more
doaj   +1 more source

The effects and mechanisms of SLC34A2 on tumorigenicity in human non-small cell lung cancer stem cells

open access: yesTumor Biology, 2016
A novel paradigm in tumor biology suggests that non-small cell lung cancer (NSCLC) growth is driven by lung cancer stem cell-like cells (LCSCs), but molecular mechanisms regulating tumorigenic and self-renewal potential of LCSCs are still unclear. Here, we aim to investigate biological function of SLC34A2 in regulating tumorigenicity of LCSCs and its ...
Peng Liu   +6 more
openaire   +3 more sources

SLC34A2 promotes neuroblastoma cell stemness via enhancement of miR‐25/Gsk3β‐mediated activation of Wnt/β‐catenin signaling

open access: yesFEBS Open Bio, 2019
Cancer stem cells contribute to cancer progression, but the mechanisms underlying neuroblastoma stem cell development are unclear. Here, we examined the roles of the transcription factor SLC34A2 in regulating the stemness of neuroblastoma cells. We found
Jian-Long Chen   +5 more
semanticscholar   +1 more source

Quantitative analysis of SLC34A2 expression in different types of ovarian tumors.

open access: yesExperimental oncology, 2011
The main purpose of this study was to estimate the SLC34A2 gene expression in normal ovary and different types of ovarian tumors.We have investigated SLC34A2 gene expression level in papillary serous, endometrioid, unspecified adenocarcinomas, benign tumors, and normal ovarian tissues using real-time PCR analysis.
Shyian, M.   +9 more
openaire   +2 more sources

Additional file 1 of Impaired phosphate transport in SLC34A2 variants in patients with pulmonary alveolar microlithiasis

open access: yes, 2022
Additional file 1 Supplementary Figures S1-S3. Fig. S1 Phosphate transport activity in Xenopus laevis oocytes 3 days after injection of water or cRNA encoding wild-type (WT) c-Myc-hNaPi-IIb. Fig. S2 Molecular identification of c-Myc hNaPi-IIb expression by Western Blot (whole blot) of lysates from Xenopus laevis oocytes injected with wild-type (WT) and
Jönsson, Åsa Lina M.   +8 more
openaire   +1 more source

An unusual late onset of pulmonary alveolar microlithiasis: A case report and literature review

open access: yesRespiratory Medicine Case Reports, 2017
Pulmonary alveolar microlithiasis (PAM) is an uncommon genetic disorder associated with alveolar cell injury. This injury is caused in most cases by inactivating mutations in SLC34A2 gene, which is responsible for the production of a sodium-dependent ...
Alexandros Stamatopoulos   +7 more
doaj   +1 more source

Pulmonary alveolar microlithiasis: review of the 1022 cases reported worldwide

open access: yesEuropean Respiratory Review, 2015
Pulmonary alveolar microlithiasis (PAM) is a rare disease characterised by the widespread intra-alveolar accumulation of minute calculi called microliths.
Giuseppe Castellana   +4 more
doaj   +1 more source

Supplementary Figures from The Dolaflexin-based Antibody–Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b

open access: green, 2023
Natalya D. Bodyak   +23 more
openalex   +2 more sources

Overexpression of SLC34A2 is an independent prognostic indicator in bladder cancer and its depletion suppresses tumor growth via decreasing c-Myc expression and transcriptional activity

open access: yesCell Death and Disease, 2017
Solute carrier family 34 member 2 (SLC34A2), a pH-sensitive sodium-dependent phosphate transporter, is associated with several human cancers. In this study, we investigate the clinical significance of SLC34A2 and its function in human bladder cancer (BC).
Wenwei Ye   +9 more
semanticscholar   +1 more source

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