Results 21 to 30 of about 2,192 (190)

Dihydrosanguinarine enhances tryptophan metabolism and intestinal immune function via AhR pathway activation in broilers [PDF]

Journal of Animal Science and Biotechnology
Background Tryptophan is essential for nutrition, immunity and neural activity, but cannot be synthesized endogenously. Certain natural products influence host health by modulating the gut microbiota to promote the production of tryptophan metabolites ...
Yue Su, Miaomiao Wang, Zhiyong Wu, Peng Huang, Jianguo Zeng   +4 more
doaj   +2 more sources

Proteolytic Enzyme Activity and mRNA Expressions of Amino Acid and Peptide Transporter Genes in Tissues of Nile tilapia (Oreochromis niloticus) Exposed to Different Salinities

Aquaculture, Fish and Fisheries
This study examined the effects of different salinity levels and exposure time on the activity of proteolytic enzymes and the mRNA expression of amino acid (AA) and peptide transporter genes in various fish tissues of Nile tilapia (Oreochromis niloticus).
Emmanuel O. Kombat, Godwin Abakari, Abdul‐Razak Salifu, Elliot H. Alhassan, Jin‐Liang Zhao   +4 more
doaj   +2 more sources

A Case Series of Cystinuric Stone Formers in Western Cape, South Africa: SLC3A1 or SLC7A9 Mutations and Phenotype

Société Internationale d’Urologie Journal, 2023
ObjectiveTo describe the genetic mutations and phenotype in the first African series of patients with cystinuria. MethodsPatients with cystinuria were recruited from a specialist metabolic renal stone clinic in Cape Town, South Africa, for DNA ...
Lisa-Ann Kaestner, John Lazarus, Azola Salukazana , Elmi Muller , Karl-Heinz Jehle   +4 more
doaj   +1 more source

Interpretation of SLC3A1 and SLC7A9 variants in cystinuria patients: The significance of the PM3 criterion and protein stability. [PDF]

Urolithiasis, 2023
Lee B, Lee SY, Han DH, Park HD.
europepmc   +2 more sources

A Novel Variant in Iranian Patient with Cystinuria: A Case Report

Iranian Journal of Public Health, 2021
Cystinuria is an autosomal recessive disorder in which the renal reabsorption of cystine, arginine, lysine and ornithine are disturbed. The two genes, the pathogenic forms of which are responsible for the disorder, are SLC7A9 and SLC3A1.
Ali Mardi, Hamed Heidary, Seyyed Mohammad Mousavi, Ghasem Khazaei, Eskandar Taghizadeh   +4 more
doaj   +1 more source

Effect of genotype on duodenal expression of nutrient transporter genes in dairy cows [PDF]

, 2013
peer-reviewedBackground Studies have shown clear differences between dairy breeds in their feed intake and production efficiencies. The duodenum is critical in the coordination of digestion and absorption of nutrients.
Buckley, Frank, Kenny, David A., Keogh, Kate, Waters, Sinead M.   +3 more
core   +3 more sources

Germline Whole-Exome Sequencing in Non-Smoker Lung Cancer Patients Reveals Pathogenic Variants in Lung Cancer Driver Genes. [PDF]

Genes Chromosomes Cancer
ABSTRACT Approximately 10%–15% of all lung cancers arise in non‐smokers. Although there are no established aetiological factors, non‐smokers with a family history of cancer have an increased risk of lung cancer, implying host genetic factors in lung cancer susceptibility. We sought to identify, in a cohort of 75 patients recruited before lung lobectomy,
Carapezza G, Minardi SP, Noci S, Pintarelli G, Zanutto S, Incarbone M, Tosi D, Dragani TA, Colombo F, Pierotti MA, Gariboldi M.   +10 more
europepmc   +2 more sources

A case of cystinuria with a heterozygous mutation presenting with recurrent multiple renal stones in a 14-year-old boy [PDF]

Childhood Kidney Diseases, 2023
Cystinuria, a genetically inherited disorder, is a rare cause of kidney stones. It is characterized by impaired transport of cystine and amino acids in the proximal renal tubule and the small intestine.
Hye Won Cho, Min Hwa Son, Hyung Eun Yim
doaj   +1 more source

Genetic and Clinical Analyses of 13 Chinese Families With Cystine Urolithiasis and Identification of 15 Novel Pathogenic Variants in SLC3A1 and SLC7A9

Frontiers in Genetics, 2020
BackgroundCystinuria is a rare genetic disorder characterized by defective renal reabsorption of cystine, ornithine, arginine, and lysine. The increased urinary excretion of cystine results in the development of cystine urolithiasis (CU).
Chuangye Li, Yongjia Yang, Yu Zheng, Fang Shen, Li Liu, Yanfang Li, Liping Li, Yaowang Zhao   +7 more
doaj   +1 more source

Gene symbol: SLC3A1. Disease: Cystinuria.

Human genetics, 2005
Hum ...
Chatzikyriakidou, A., Sofikitis, N., Georgiou, I.   +2 more
  +23 more sources