Results 1 to 10 of about 200,456 (163)

The role of system A for neutral amino acid transport in the regulation of cell volume [PDF]

Molecular Membrane Biology, 2001
System A is a secondary active, sodium dependent transport system for neutral amino acids. Strictly coupled with Na,K-ATPase, its activity determines the size of the intracellular amino acid pool, through a complex network of metabolic reaction and exchange fluxes. Many hormones and drugs affect system A activity in specific cell models or tissues.
Ovidio Bussolati, Roberto Sala, Valeria Dall'asta   +2 more
exaly   +5 more sources

Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A

Biochimica Et Biophysica Acta - Biomembranes, 2001
We report here on the cloning and functional characterization of the third subtype of amino acid transport system A, designated ATA3 (amino acid transporter A3), from a human liver cell line. This transporter consists of 547 amino acids and is structurally related to the members of the glutamine transporter family.
Mitsuru Sugawara, Vadivel Ganapathy, Puttur D Prasad   +2 more
exaly   +3 more sources

Structure-Affinity Relationships of Substrates for the Neutral Amino Acid Transport System in Rabbit Ileum [PDF]

Journal of General Physiology, 1974
The apparent affinities of various amino acids for the neutral amino acid transport system in rabbit ileum were determined by measuring the inhibition of L-methionine-14C influx across the brush border membrane. The apparent affinity was very low for compounds lacking an α-amino group, compounds with the α-hydrogen substituted by a methyl group, D ...
R L, Preston, J F, Schaeffer, P F, Curran   +2 more
exaly   +3 more sources

Amino Acid Transporters as Potential Therapeutic Targets in Thyroid Cancer [PDF]

Endocrinology and Metabolism, 2020
Thyroid cancer cells have a high amino acid demand for proliferation, invasion, and metastasis. Amino acids are taken up by thyroid cancer cells, both thyroid follicular cell and thyroid parafollicular cells (commonly called “C-cells”), via amino acid ...
Keisuke Enomoto, Muneki Hotomi
doaj   +1 more source

The identification of neutral amino acid transport systems [PDF]

Experimental Physiology, 1990
Dans cet article de synthese on donne les caracteristiques des systemes de transport des acides amines neutres dans les cellules non epitheliales et dans les cellules epitheliales de l'intestin grele, du rein, du placenta, des glandes salivaires et de la barriere hemato-encephalique.
G A, Barker, J C, Ellory
openaire   +2 more sources

Characterization and Regulation of the Amino Acid Transporter SNAT2 in the Small Intestine of Piglets. [PDF]

PLoS ONE, 2015
The sodium-dependent neutral amino acid transporter 2 (SNAT2), which has dual transport/receptor functions, is well documented in eukaryotes and some mammalian systems, but has not yet been verified in piglets.
Guangran Li, Jianjun Li, Bie Tan, Jing Wang, Xiangfeng Kong, Guiping Guan, Fengna Li, Yulong Yin   +7 more
doaj   +1 more source

Effect of mannan-rich fractions and a mixture of sodium butyrate and zinc proteinate on performance, intestinal morphometry, and gene expression in broilers

Italian Journal of Animal Science, 2023
This study evaluated the effects of isolated or combined prebiotics blended with sodium butyrate and zinc proteinate on performance, intestinal morphometry, and expression of genes associated with nutrient transport and immune response in broilers. 1,400
M. A. S. Silva, V. Ribeiro Júnior, C. M. Silva, L. F. C. Silva, A. P. Del Vesco, G. M. Oliveira Junior, A. A. Calderano, F. C. Tavernari, A. Corassa, C. O. Brito   +9 more
doaj   +1 more source

Third system for neutral amino acid transport in a marine pseudomonad [PDF]

Journal of Bacteriology, 1977
Uptake of leucine by the marine pseudomonad B-16 is an energy-dependent, concentrative process. Respiratory inhibitors, uncouplers, and sulfhydryl reagents block transport. The uptake of leucine is Na+ dependent, although the relationship between the rate of leucine uptake and Na+ concentration depends, to some extent, on the ionic strength of the ...
S M, Pearce, V A, Hildebrandt, T, Lee
openaire   +2 more sources

Reactions of neutral amino acids plus Na⁺ with a cationic amino acid transport system [PDF]

FEBS Letters, 1969
Before we could understand the transport interactions between the neutral and the basic amino acids, we needed to answer four questions: 1. To what extent do diamino acids actually react with transport systems in their neutral forms? First, a,fl-diamino propionic acid, pK; = 6.7, was shown to behave in transport almost entirely as a neutral amino acid,
Christensen, Halvor N., Handlogten, Mary E.   +1 more
openaire   +3 more sources

Na ⁺ -FACILITATED REACTIONS OF NEUTRAL AMINO ACIDS WITH A CATIONIC AMINO ACID TRANSPORT SYSTEM [PDF]

Proceedings of the National Academy of Sciences, 1969
The predominant basis for transport interactions between neutral and cationic amino acids in the Ehrlich ascites-tumor cell and the rabbit reticulocyte has been identified as a reaction of the neutral amino acid plus Na + with the cationic amino acid transport system. This reaction is revealed both by a Na
H N, Christensen, M E, Handlogten, E L, Thomas   +2 more
openaire   +2 more sources