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Promising Approaches to Optimize the Biological Properties of the Antimicrobial Peptide Esculentin-1a(1–21)NH2: Amino Acids Substitution and Conjugation to Nanoparticles [PDF]

open access: yesFrontiers in Chemistry, 2017
Antimicrobial peptides (AMPs) represent an interesting class of molecules with expanding biological properties which make them a viable alternative for the development of future antibiotic drugs.
Bruno Casciaro   +3 more
doaj   +4 more sources

Quantum chemical study of molecular properties of small branched-chain amino acids in water [PDF]

open access: yesAmino Acids
Four aliphatic amino acids—α-aminobutyric acid (AABA), β-aminobutyric acid (BABA), α-aminoisobutyric acid (AAIBA) and β-aminoisobutyric acid (BAIBA) were investigated in water as a solvent by two quantum chemical methods.
Roman Boča   +4 more
doaj   +2 more sources

A Journey into the Blue: Current Knowledge and Emerging Insights into Marine-Derived Peptaibols [PDF]

open access: yesMarine Drugs
Peptaibols represent a large family of membrane-active, linear fungal peptides, with variable lengths from 5 to 21 α–amino acid residues. As products of nonribosomal peptide synthetase (NRPS) biosynthetic machinery, they encompass several non ...
Claudia Finamore   +4 more
doaj   +2 more sources

Identification of blood biomarkers associated with hepatic lipid accumulation in aging laying hens with fatty liver [PDF]

open access: yesPoultry Science
Fatty Liver Hemorrhagic Syndrome (FLHS) is a metabolic disorder characterized by excessive hepatic triglycerides (TG) accumulation, primarily affecting high-producing, caged laying hens.
Zheng Wang   +5 more
doaj   +2 more sources

Roseabol A, a New Peptaibol from the Fungus Clonostachys rosea

open access: yesMolecules, 2021
A new 11 amino acid linear peptide named roseabol A (1) and the known compound 13-oxo-trans-9,10-epoxy-11(E)-octadecenoic acid (2) were isolated from the fungus Clonostachys rosea. Combined NMR and MS analysis revealed that roseabol A (1) contained amino
Chang-Kwon Kim   +8 more
doaj   +1 more source

A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms

open access: yesMicroorganisms, 2020
The discovery of liquid water at several locations in the solar system raises the possibility that microbial life may have evolved outside Earth and as such could be accidently introduced into the Earth’s ecosystem.
Katja Schaefer   +9 more
doaj   +1 more source

Ameliorative effects of functional crude-chalaza hydrolysates on the hepatosteatosis development induced by a high-fat diet

open access: yesPoultry Science, 2021
Approximately 400 metric tons of egg chalazae, a byproduct in the liquid-egg processing plant, are produced yearly but always regarded as a waste in Taiwan.
Jr-Wei Chen   +5 more
doaj   +1 more source

Application of α-aminoisobutyric acid and β-aminoisobutyric acid inhibits pericarp browning of harvested longan fruit [PDF]

open access: yesChemistry Central Journal, 2015
Pericarp browning is a critical problem resulting in reduced commercial value and shelf life of longan fruit.Two non-protein amino acids, α-aminoisobutyric acid (AIB) and β-aminoisobutyric acid (BAIB) at 100 and 1 mM were applied to longan fruit prior to storage for up to 8 days at 25 °C respectively.
Wang, Hui   +4 more
openaire   +2 more sources

Urinary beta-aminoisobutyric acid excretion in thalassaemia [PDF]

open access: yesJournal of Clinical Pathology, 1969
The quantity of beta-aminoisobutyric acid (BAIB) excreted in the urine of patients with an intact spleen suffering from thalassaemia major appears to be proportional to the number of the circulating normoblasts and inversely proportional to the haemoglobin level. After splenectomy only minute amounts of BAIB are excreted.
P, Fessas, A, Koniavitis, P M, Zeis
openaire   +2 more sources

Elevated circulating level of β-aminoisobutyric acid (BAIBA) in heart failure patients with type 2 diabetes receiving sodium-glucose cotransporter 2 inhibitors

open access: yesCardiovascular Diabetology, 2022
Aims The mechanism by which a sodium-glucose cotransporter inhibitor (SGLT2i) induces favorable effects on diabetes and cardiovascular diseases including heart failure (HF) remains poorly understood.
Satoshi Katano   +15 more
doaj   +1 more source

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