Results 1 to 10 of about 3,558 (167)

Quantum chemical study of molecular properties of small branched-chain amino acids in water [PDF]

Amino Acids
Four aliphatic amino acids—α-aminobutyric acid (AABA), β-aminobutyric acid (BABA), α-aminoisobutyric acid (AAIBA) and β-aminoisobutyric acid (BAIBA) were investigated in water as a solvent by two quantum chemical methods.
Roman Boča, Žofia Rádiková, Juraj Štofko, Beata Vranovičová, Cyril Rajnák   +4 more
doaj   +2 more sources

Causal role of genetically predicted impairment of branched-chain amino acid catabolism on insulin secretion and insulin resistance in type 2 diabetes. [PDF]

Diabetes Obes Metab
Abstract Background Elevated branched‐chain amino acids (BCAAs; leucine, valine, isoleucine) are linked to type 2 diabetes (T2D) risk, characterised by defective insulin secretion in pancreatic β‐cell and peripheral insulin resistance. Causative interaction between BCAA metabolism and these two diabetic pathogenesis remains unclear.
Zhou X, Lu J, Wang Z, Cheng KK, Li GH.
europepmc   +2 more sources

A Novel Multimodal LC-MS/MS Panel for the Comprehensive Diagnosis of Neurometabolic Disorders in CSF. [PDF]

J Inherit Metab Dis
ABSTRACT Metabolic testing of cerebrospinal fluid (CSF) is essential for early diagnosis of neurometabolic disorders. However, the large number of differential diagnoses, the phenotypic variance within a clinical picture, and the disease rarity complicate targeted metabolic diagnostics.
Christ S, Rossmann J, Richter S, Garbade S, Klinke G, Blau N, Hoffmann GF, Okun JG, Opladen T.   +8 more
europepmc   +2 more sources

Roseabol A, a New Peptaibol from the Fungus Clonostachys rosea

Molecules, 2021
A new 11 amino acid linear peptide named roseabol A (1) and the known compound 13-oxo-trans-9,10-epoxy-11(E)-octadecenoic acid (2) were isolated from the fungus Clonostachys rosea. Combined NMR and MS analysis revealed that roseabol A (1) contained amino
Chang-Kwon Kim, Lauren R. H. Krumpe, Emily Smith, Curtis J. Henrich, Isaac Brownell, Karen L. Wendt, Robert H. Cichewicz, Barry R. O’Keefe, Kirk R. Gustafson   +8 more
doaj   +1 more source

A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms

Microorganisms, 2020
The discovery of liquid water at several locations in the solar system raises the possibility that microbial life may have evolved outside Earth and as such could be accidently introduced into the Earth’s ecosystem.
Katja Schaefer, Ivy M. Dambuza, Sergio Dall’Angelo, Raif Yuecel, Marcel Jaspars, Laurent Trembleau, Matteo Zanda, Gordon D. Brown, Mihai G. Netea, Neil A. R. Gow   +9 more
doaj   +1 more source

Application of α-aminoisobutyric acid and β-aminoisobutyric acid inhibits pericarp browning of harvested longan fruit [PDF]

Chemistry Central Journal, 2015
Pericarp browning is a critical problem resulting in reduced commercial value and shelf life of longan fruit.Two non-protein amino acids, α-aminoisobutyric acid (AIB) and β-aminoisobutyric acid (BAIB) at 100 and 1 mM were applied to longan fruit prior to storage for up to 8 days at 25 °C respectively.
Wang, Hui, Zhi, Wei, Qu, Hongxia, Lin, Hetong, Jiang, Yueming   +4 more
openaire   +2 more sources

Ameliorative effects of functional crude-chalaza hydrolysates on the hepatosteatosis development induced by a high-fat diet

Poultry Science, 2021
Approximately 400 metric tons of egg chalazae, a byproduct in the liquid-egg processing plant, are produced yearly but always regarded as a waste in Taiwan.
Jr-Wei Chen, Yi-Ling Lin, Yi-Hsieng Samuel Wu, Sheng-Yao Wang, Chung-Hsi Chou, Yi-Chen Chen   +5 more
doaj   +1 more source

Urinary beta-aminoisobutyric acid excretion in thalassaemia [PDF]

Journal of Clinical Pathology, 1969
The quantity of beta-aminoisobutyric acid (BAIB) excreted in the urine of patients with an intact spleen suffering from thalassaemia major appears to be proportional to the number of the circulating normoblasts and inversely proportional to the haemoglobin level. After splenectomy only minute amounts of BAIB are excreted.
P, Fessas, A, Koniavitis, P M, Zeis
openaire   +2 more sources

Elevated circulating level of β-aminoisobutyric acid (BAIBA) in heart failure patients with type 2 diabetes receiving sodium-glucose cotransporter 2 inhibitors

Cardiovascular Diabetology, 2022
Aims The mechanism by which a sodium-glucose cotransporter inhibitor (SGLT2i) induces favorable effects on diabetes and cardiovascular diseases including heart failure (HF) remains poorly understood.
Satoshi Katano, Toshiyuki Yano, Hidemichi Kouzu, Ryohei Nagaoka, Ryo Numazawa, Kotaro Yamano, Yusuke Fujisawa, Katsuhiko Ohori, Nobutaka Nagano, Takefumi Fujito, Ryo Nishikawa, Wataru Ohwada, Masaki Katayose, Tatsuya Sato, Atsushi Kuno, Masato Furuhashi   +15 more
doaj   +1 more source

Skeletal muscles and gut microbiota-derived metabolites: novel modulators of adipocyte thermogenesis

Frontiers in Endocrinology, 2023
Obesity occurs when overall energy intake surpasses energy expenditure. White adipose tissue is an energy storage site, whereas brown and beige adipose tissues catabolize stored energy to generate heat, which protects against obesity and obesity ...
Yi Tang, Yi Tang, Ya-Di Wang, Yuan-Yuan Wang, Zhe-Zhen Liao, Xin-Hua Xiao   +5 more
doaj   +1 more source