Executive Summary: The 2026 British Society for Rheumatology guideline for the management of children, young people and adults with systemic lupus erythematosus. [PDF]
Md Yusof MY +37 more
europepmc +1 more source
Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu +9 more
wiley +1 more source
Performance of common fetal growth standards in pregnancies affected by systemic lupus erythematosus. [PDF]
Barros ACRP +6 more
europepmc +1 more source
Stable and Functional Regulatory T Cells for Adoptive Cell Therapy
Deprivation of CD28 signaling combined with CDK8/19 inhibition induces stable iTregs with demethylation of Treg‐DRs. Re‐stimulation of these iTregs with additional agents further enhances their suppressive function. The generated S/F‐iTregs suppress inflammation in vivo, and subset of the suppressed Tconvs is converted into de novo pTregs, contributing
Norihisa Mikami
wiley +1 more source
How Epstein Barr virus shapes lupus autoimmunity: mechanistic insights and therapeutic perspectives. [PDF]
Miskovic R +4 more
europepmc +1 more source
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu +9 more
wiley +1 more source
The 2026 British Society for Rheumatology guideline for the management of children, young people and adults with systemic lupus erythematosus. [PDF]
Md Yusof MY +37 more
europepmc +1 more source
Dual role of spreading depolarization in an epileptic focus
Abstract Objective Spreading depolarizations (SDs) are often associated with epileptic discharges. Although SDs are traditionally thought to contribute to postictal depression and termination of epileptic discharges, seizures may also occur during SDs or may even follow SDs, suggesting that interactions between SD and seizures are more complex.
Daria Vinokurova +3 more
wiley +1 more source
The landscape of cellular immune alteration in systemic lupus erythematosus. [PDF]
Xiao J +11 more
europepmc +1 more source
The dynamic functional connectivity peak index: Detection of interictal epileptic activity with fMRI
Abstract Objective Epileptogenic zone (EZ) localization is crucial for surgical treatment of patients with medication‐resistant epilepsy. Although simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) can detect interictal discharges for EZ localization, clinical adoption is limited by the need for specialized ...
Lucas E. Sainburg +9 more
wiley +1 more source

