Results 131 to 140 of about 82,336 (259)

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, Accepted Article.
Background Type I interferonopathies are heterogeneous diseases driven by dysregulated IFN‐I signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. Objective To characterize the clinical, immunological, genetic, molecular profiles of patients with suspected enhanced IFN‐I signaling, and assess ...
Ismail Yaz, Seza Ozen, Hacer N. Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet E. Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet O. Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Application of 3D scanning technology in Royal Malaysian Air Force Industrial Revolution 4.0‐based aircraft maintenance

IET Networks, EarlyView., 2022
Abstract 3D scanning is rapidly becoming a key maintenance tool. Aerospace was a pioneer in adopting 3D scanning technology because aircraft manufacture and maintenance require precision. Monitoring deterioration, removing components for maintenance, and verifying covert operations are not practical or helpful without technology.
T. Nanthakumaran Thulasy, Puteri N. E. Nohuddin, Istas Fahrurrazi Nusyirwan, Mohd Hanafi Ahmad Hijazi, Musaddak Maher Abdul Zahra   +4 more
wiley   +1 more source

Impact of Systemic Lupus Erythematosus on Short-Term and Long-Term Outcomes in Total Knee Arthroplasty: A National Database Propensity-Matched Cohort Study. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Shafau AL, Suhrawardy A, Alazawi H, Almaat A, Yazdani F, Hasan A, Kazi S, Diab O, Diab A, Saleh KJ, Darwiche H.   +10 more
europepmc   +1 more source

IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay, Alexia Orellana, George C. Tsokos, Rhea Bhargava   +3 more
wiley   +1 more source

Belimumab as a possible treatment for SLE-associated pulmonary arterial hypertension: the experience from a single centre. [PDF]

Lupus Sci Med
Wu Q, Zhou Z, Ye H, Zhang M, Sun X, Wang Q.   +5 more
europepmc   +1 more source

DNA (cytosine‐5)‐methyltransferase 3A (Dnmt3a) mutations limit normal and autoreactive CD4+ T follicular helper responses and attenuate T cell‐driven joint inflammation

Arthritis &Rheumatology, Accepted Article.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased inflammatory markers. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen, Sanjaykumar Boddul, Zhaojun Li, Zsolt Kasza, Marlene Schülein, Bruno Raposo, Karine Chemin, Per‐Johan Jakobsson, Alexander Espinosa, Lars Klareskog, Fredrik Wermeling   +10 more
wiley   +1 more source

Systemic lupus erythematosus-driven accelerated atherosclerosis: the immune-metabolic-vascular axis and therapeutic implications. [PDF]

Front Immunol
Jiang M, Zhang F, Ren M, Li Z, Xie Z, Sun J.   +5 more
europepmc   +1 more source

Deep Immunophenotyping Reveals Distinct Immune Signatures in Axial Spondyloarthritis and Psoriatic Arthritis

Arthritis &Rheumatology, Accepted Article.
Objective Axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are overlapping yet distinct conditions within the spondyloarthritis (SpA) spectrum. As divergent immunophenotypes may influence disease course and therapeutic response, we compared immune cell subsets, cytokine profiles, and inflammatory mediators.
Natalie Frede, Nils Craig‐Müller, Silke Kohrt, Marei‐Theresa Bott, Ulrich Salzer, Ana Cecilia Venhoff, Jens Thiel, Julia Frede, Reinhard E. Voll, Marta Rizzi, Raquel Lorenzetti, Nils Venhoff   +11 more
wiley   +1 more source

Stage-resolved mapping of RP105 (CD180)-negative B cells reveals residual plasmablast-lineage skewing in SLE: a cross-sectional study. [PDF]

Lupus Sci Med
Kanagawa A, Maruyama A, Shibuta T, Akahoshi M, Soejima S, Tada Y, Koarada S.   +6 more
europepmc   +1 more source

Patellar Tendon Repair With Gracilis Autograft Augmentation and Anchor Fixation

Arthroscopy Techniques, EarlyView.
Abstract Patellar tendon rupture is a severe injury that disrupts knee extensor continuity and requires prompt surgical management. Although primary repair remains the standard treatment, isolated suture repair may be insufficient in cases of poor tissue quality or high mechanical demand, making augmentation necessary.
Luis Henrique Longo, Bruno Dada Gulini, Marcos Paulo Tercziany Vanzin, Fernando Martins Rosa, Luca Eiji Sohn Sato, Luis Antonio de Ridder Bauer, Edmar Stieven Filho   +6 more
wiley   +1 more source