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Infections and SLE

open access: yesAutoimmunity, 2005
Viral and bacterial infections may serve as an environmental trigger for the development or exacerbation of systemic lupus erythematosus (SLE) in the genetically predetermined individual. In addition, SLE patients are more prone to develop common (pneumonia, urinary tract infection, cellulitis, sepsis), chronic (tuberculosis), and opportunistic ...
Gisele Zandman-Goddard
exaly   +3 more sources
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SLE and Infections

Clinical Reviews in Allergy & Immunology, 2003
Infections are common in systemic lupus erythematosus (SLE), and remain a source of mortality. The types of infections (such as pneumonia, urinary tract infection, cellulitis, and sepsis) in SLE patients are similar to the general population and include the same pathogens (Gram-positive and Gram-negative).
Gisele, Zandman-Goddard   +1 more
openaire   +2 more sources

SLE dacryoadenitis

Orbit, 2018
In systemic lupus erythematosus, ophthalmic manifestations are noted in up to one-third of patients. We describe a patient with an unusual initial presentation of this disorder.
Yu-Chieh, Hung   +4 more
openaire   +2 more sources

Plasmapheresis in SLE

Clinics in Rheumatic Diseases, 1982
SUMMARY AND CONCLUSIONS The growing number of anecdotal reports on the effect of plasmapheresis in patients with active SLE suggests that plasmapheresis, particularly in combination with cytotoxic drugs, merits further exploration as a therapeutic modality.
openaire   +2 more sources

New Therapies in SLE

Recent Patents on Inflammation & Allergy Drug Discovery, 2008
The therapy of systemic lupus erythematosus (SLE), a systemic autoimmune disease of unknown aetiology, is significantly complicated by the diversity of disease manifestations and by a variety of complex immune abnormalities. Recent preclinical studies have shown the therapeutic efficacy of several drugs and/or new compounds, some of which have been ...
FERRERA, FRANCESCA   +6 more
openaire   +4 more sources

Is it SLE?

Best Practice & Research Clinical Rheumatology, 2002
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease, as yet of unknown aetiology, with diverse clinical manifestations and a variable course and prognosis. The diagnosis is based on recognizing the overall pattern of clinical and laboratory abnormalities.
openaire   +2 more sources

Genetics of SLE in mice

Springer Seminars in Immunopathology, 2006
Genetic studies in spontaneous, induced, and gene-manipulated mouse models of SLE have provided significant insights into the potential number and diversity of genes that can promote, resist, and modify lupus susceptibility. Novel genes and mechanisms of disease pathogenesis have also been identified.
Dwight H, Kono   +1 more
openaire   +2 more sources

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