Unrecognised sleep disturbances in patients with cirrhosis diagnosed with a portable electroencephalogram device. [PDF]
Uchiyama A +13 more
europepmc +1 more source
Ageing‐related modification of sleep and breathing in orexin‐knockout narcoleptic mice
Summary Narcolepsy type‐1 (NT1) is a lifelong sleep disease, characterised by impairment of the orexinergic system, with a typical onset during adolescence and young adulthood. Since the wake–sleep cycle physiologically changes with ageing, this study aims to compare sleep patterns between orexin‐knockout (KO) and wild type (WT) control mice at ...
Stefano Bastianini +7 more
wiley +1 more source
Functional Suppression of CLOCK Activity in Ventromedial Hypothalamic Prodynorphin Neurons Alters Locomotor Activity and Rapid Eye Movement Sleep. [PDF]
He T, Wang X.
europepmc +1 more source
Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli +12 more
wiley +1 more source
Differential motor signatures in isolated and narcolepsy-related REM sleep behaviour disorder: a preliminary study. [PDF]
Drakatos P +13 more
europepmc +1 more source
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont +5 more
wiley +1 more source
Sex‐based disparities in dopamine agonist response in patients with restless legs syndrome
Summary This study aimed to investigate sex‐related differences in the response to ropinirole and pramipexole in patients with restless legs syndrome (RLS). By analysing clinical parameters and polysomnographic (PSG) findings, we sought to elucidate the potential factors related to sex disparities modulating treatment responses and sleep quality in RLS.
Maria P. Mogavero +9 more
wiley +1 more source
The Hypno-PC: uncovering sleep dynamics through principal component analysis and hidden Markov modeling of electrophysiological signals. [PDF]
Guendelman M, Shriki O.
europepmc +1 more source
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias +5 more
wiley +1 more source
Home-Based REM Sleep Without Atonia in Patients with Parkinson's Disease: A Post Hoc Analysis of the ZEAL Study. [PDF]
Kataoka H +9 more
europepmc +1 more source

