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Rapid eye movement (REM) sleep plays a crucial role in brain functions such as memory consolidation and mood regulation. Alterations in REM sleep and REM sleep behaviour disorders are early biomarkers of neurodegenerative disorders. The microstructure of
Kiran K G Ravindran, Derk-Jan Dijk
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Characteristic Effects of Anti-dementia Drugs on Rat Sleep Patterns
The present study was undertaken to clarify the effects of anti-dementia drugs on sleep pattern in rats. Electrodes were chronically implanted into the frontal cortex and the dorsal neck muscle of rats for the electroencephalogram (EEG) and ...
Takayuki Ishida, Chiaki Kamei
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Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 1, a pharmacokinetic/pharmacodynamic comparison with paroxetine in healthy men [PDF]
We compared the effect of vortioxetine, paroxetine and placebo after three days of dosing on sleep architecture. This was a randomised, double-blind, four-way crossover, placebo-controlled, multiple-dose study in 24 healthy young men.
Areberg, J +4 more
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Objective Rapid Eye Movement (REM) rebound is a polysomnographic phenomenon where a substantial increase in REM sleep is noted in patients with untreated obstructive sleep apnea (OSA) when first undergoing continuous positive airway pressure (CPAP ...
Gaurav Nigam +2 more
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Increased cortical excitability after selective REM sleep deprivation in healthy humans: a transcranial magnetic stimulation study [PDF]
REM sleep has antiepileptogenic properties whereas, its loss is known to have a proconvulsive role. However, the mechanisms underlying the proepileptogenic effects of REM sleep deprivation are yet not fully understood.
Albanese, M +6 more
core +1 more source
REM Sleep Characteristics in Narcolepsy and REM Sleep Behavior Disorder [PDF]
To assess the presence of polysomnographic characteristics of REM sleep behavior disorder (RBD) in narcolepsy; and to quantify REM sleep parameters in patients with narcolepsy, in patients with "idiopathic" RBD, and in normal controls.Sleep laboratory studySixteen patients with narcolepsy and cataplexy matched for age and sex with 16 patients with ...
Yves, Dauvilliers +5 more
openaire +2 more sources
The lateral hypothalamus contains neurons producing orexins that promote wakefulness and suppress REM sleep as well as neurons producing melanin-concentrating hormone (MCH) that likely promote REM sleep.
Fumito Naganuma +5 more
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Rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by disrupting motor enactments during REM sleep, but also cognitive impairments across several domains.
Amandine Valomon +7 more
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Neuronal avalanches differ from wakefulness to deep sleep - evidence from intracranial depth recordings in humans [PDF]
Neuronal activity differs between wakefulness and sleep states. In contrast, an attractor state, called self-organized critical (SOC), was proposed to govern brain dynamics because it allows for optimal information coding.
Le Van Quyen, Michel +3 more
core +3 more sources
Automated scoring of pre-REM sleep in mice with deep learning
Reliable automation of the labor-intensive manual task of scoring animal sleep can facilitate the analysis of long-term sleep studies. In recent years, deep-learning-based systems, which learn optimal features from the data, increased scoring accuracies ...
Niklas Grieger +4 more
doaj +1 more source

