Results 51 to 60 of about 49,955 (299)
Melanin-concentrating hormone (MCH): a new sleep factor?
Frontiers in Neurology, 2011 Neurons that utilize the neuropeptide melanin-concentrating hormone (MCH) as a neuromodulator are mainly located in the lateral hypothalamus and the incerto-hypothalamic area, and have widespread projections throughout the brain.
Pablo eTorterolo +2 more
doaj +1 more source
A study on sleep apnea in patients with abnormal sewda type of depression
Traditional Medicine and Modern Medicine, 2020 Objective: To preliminarily investigate the clinical features and PSG in abnormal sewda-type depressive insomnia. Methods: A total of 127 abnormal sewda-type depressive insomnia patients were evaluated with overnight PSG, and 32 normal participants were ...
Aman Gul +7 more
doaj +1 more source
A Hypothalamic Switch for REM and Non-REM Sleep [PDF]
Neuron, 2018 Rapid eye movement (REM) and non-REM (NREM) sleep are controlled by specific neuronal circuits. Here we show that galanin-expressing GABAergic neurons in the dorsomedial hypothalamus (DMH) comprise separate subpopulations with opposing effects on REM versus NREM sleep.
Chen, Kai-Siang +6 more
openaire +4 more sources
The Natural History of Insomnia: Acute Insomnia and First-onset Depression
, 2013 Study Objectives: While many studies have examined the association between insomnia and depression, no studies have evaluated these associations 1) within a narrow time frame, 2) with specific reference to acute & chronic insomnia, and 3) using ...
Michael L. Perlis +18 more
core +1 more source
Essential roles of GABA transporter-1 in controlling rapid eye movement sleep and in increased slow wave activity after sleep deprivation. [PDF]
PLoS ONE, 2013 GABA is the major inhibitory neurotransmitter in the mammalian central nervous system that has been strongly implicated in the regulation of sleep. GABA transporter subtype 1 (GAT1) constructs high affinity reuptake sites for GABA and regulates GABAergic
Xin-Hong Xu +6 more
doaj +1 more source
Antidepressants and their effect on sleep
, 2005 Given the relationship between sleep and depression, there is inevitably going to be an effect of antidepressants on sleep. Current evidence suggests that this effect depends on the class of antidepressant used and the dosage.
Mayers, Andrew G. +3 more
core +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Children, 2022 Objective: Insomnia and daytime behavioral problems are common issues in pediatric autism spectrum disorder (ASD), yet specific underlying relationships with NonRapid Eye Movement sleep (NREM) and Rapid Eye Movement (REM) sleep architecture are ...
Jennifer Nguyen +4 more
doaj +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Orexin-1 receptor blockade dysregulates REM sleep in the presence of orexin-2 receptor antagonism
Frontiers in Neuroscience, 2014 In accordance with the prominent role of orexins in the maintenance of wakefulness via activation of orexin-1 (OX1R) and orexin-2 (OX2R) receptors, various dual OX1/2R antagonists have been shown to promote sleep in animals and humans.
Christine eDugovic +5 more
doaj +1 more source