Results 71 to 80 of about 24,181 (268)

Association of sleep disturbances with diminished ovarian reserve in women undergoing infertility treatment

Scientific Reports
With an aging population seeking infertility treatment, diminished ovarian reserve (DOR) is a prevalent indication for assisted reproductive technology (ART).
Xue-Fen Cai, Bi-Ying Wang, Jian-Ming Zhao, Mei-Xin Nian, Qi-Chang Lin, Jie-Feng Huang   +5 more
doaj   +1 more source

SUDEP and mortality in developmental and epileptic encephalopathies: A meta‐analysis of randomized clinical trials and extension studies

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are associated with high premature mortality and increased risk of sudden unexpected death in epilepsy (SUDEP). However, epidemiological data remain limited, particularly for specific syndromes such as Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), and infantile epileptic ...
Pierludovico Moro, Maria Sole Borioni, Adolfo Mazzeo, Enrico Cocchi, Carlo Di Bonaventura, Emanuele Cerulli Irelli   +5 more
wiley   +1 more source

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source

Triggered Calcium Lightning Programs Cochlear Development

Exploration, EarlyView.
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma, Hai‐Peng Wang, Yu‐Meng Jiang, Ke Lai, Ming‐Xian Li, Zhen Zhang, Li‐Na Gong, Jing‐Wei Lai, Kai‐Ming Su, Lu‐Yang Wang, Hui Wang, Shan‐Kai Yin, Hao He, Hai‐Bo Shi   +13 more
wiley   +1 more source

Monitoring and assessment for obstructive sleep apnea

FlexMat, EarlyView.
This review systematically classifies Obstructive Sleep Apnea (OSA) monitoring indicators into three categories: physical, biochemical, and electrophysiological indicators, and lists several methods for each category. Abstract Obstructive sleep apnea (OSA) is a common chronic sleep‐disordered breathing disease characterized by recurrent upper airway ...
Yaowen Xu, Feifei Lin, Shujiao Chen, Zhen You, Shujing Zhu, Weiwei Zhao, Qiang Zhao   +6 more
wiley   +1 more source

Conformal immunomodulatory hydrogels for the treatment of otitis media

Journal of Nanobiotechnology
Otitis media (OM), a condition stemming from the proliferation of various bacteria within the tympanic cavity (TC), is commonly addressed through the administration of ofloxacin (OFL), a fluoroquinolone antibiotic.
Yuefan Jin, Yueyi Shang, Cuiping Wu, Zhengnong Chen, Haibo Shi, Hui Wang, Linpeng Li, Shankai Yin   +7 more
doaj   +1 more source

Longitudinal associations between sleepiness and sleep disturbances across pregnancy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Although sleep disturbances increase during pregnancy, sleepiness does not appear to follow a similar trajectory. Given that the relationship between sleep disturbances and sleepiness during pregnancy is understudied, we examined their associations to determine whether these relationships strengthen with advancing gestation.
Linda Aukia, Laura Perasto, Linnea Karlsson, Hasse Karlsson, E. Juulia Paavonen, Päivi Polo‐Kantola   +5 more
wiley   +1 more source

Measurement of social and emotional wellbeing and mental health outcomes in first nations children: A systematic review

JCPP Advances, EarlyView.
Abstract Background There is a critical lack of reliable, high‐quality epidemiological data on mental health and/or social and emotional wellbeing (SEWB) outcomes for First Nations children, partly, due to the limited availability of culturally valid assessment tools. This review aims to assess the cultural validity of mental health and SEWB assessment
Maddison O’Gradey‐Lee, Emma A. McDermott, Lizel‐Antoinette Bertie, Clinton Schultz, Jennifer L. Hudson   +4 more
wiley   +1 more source

pH-Responsive Liposome–Hydrogel Composite Accelerates Nasal Mucosa Wound Healing

Pharmaceutics
Objectives: Nasal mucosa wound healing faces challenges such as acidic microenvironments and bacterial proliferation. Persistent mucosal defects predispose to complications such as nasal septal perforation.
Yingchao Yang, Jingyi Chen, Shengming Wang, Yaxin Zhu, Yao Wang, Yan Chen, Mingjiang Xia, Ming Yang, Hongliang Yi, Kaiming Su   +9 more
doaj   +1 more source

Gingival inflammation and plaque accumulation affect therapeutic outcomes in patients with acne vulgaris

Journal of Periodontology, EarlyView.
Abstract Background We hypothesized that acne vulgaris (AV) and gingivitis were associated through systemic inflammatory mechanisms, sharing common etiological factors. This study aimed to identify the association between AV and gingivitis and to assess changes in acne severity in relation to changes in the plaque index (PI).
Ömer Faruk Okumuş, Mustafa Yazıcı, Alpdoğan Kantarci   +2 more
wiley   +1 more source